Towards precise diagnosis time profile of ultrafast electron bunch trains using orthogonal terahertz streak camera.

Ultrafast electron microbunch trains have broad applications in which the individual bunch length and the bunch-to-bunch interval are critical parameters that need to be precisely diagnosed. However, directly measuring these parameters remains challenging. This paper presents an all-optical method that simultaneously measures the individual bunch length and the bunch-to-bunch spacing through an orthogonal THz-driven streak camera.

Correction: Enhanced brightness and electron affinity of terrylenediimide with sulfone-bridged substituents on the bay region.

Correction for 'Enhanced brightness and electron affinity of terrylenediimide with sulfone-bridged substituents on the bay region' by Yan Zhang et al., Chem. Commun.

Enhanced brightness and electron affinity of terrylenediimide with sulfone-bridged substituents on the bay region.

Terrylenediimide with electron-withdrawing groups (TDI4SF) was synthesized by the attachment of sulfone substituents on the bay region of terrylenediimide. The electron-withdrawing sulfone groups enhance the electron affinity, reduce the LUMO level to -4.37 eV, and endow TDI with excellent anti-oxidation ability.

Alternative polyadenylation dependent function of splicing factor SRSF3 contributes to cellular senescence.

Down-regulated splicing factor SRSF3 is known to promote cellular senescence, an important biological process in preventing cancer and contributing to individual aging, via its alternative splicing dependent function in human cells. Here we discovered alternative polyadenylation (APA) dependent function of SRSF3 as a novel mechanism explaining SRSF3 downregulation induced cellular senescence. Knockdown of resulted in preference usage of proximal poly(A) sites and thus global shortening of 3' untranslated regions (3' UTRs) of mRNAs.

Bid is a positive regulator for donor-derived lymphoid cell regeneration in γ-irradiated recipients.

Objective: Hematopoietic regeneration is regulated by cell survival proteins, such as the Bcl-2 family. Bid, a BH3-only protein of the Bcl-2 family, has multiple cellular functions and is involved in a variety of physiological or pathological conditions. We attempted to define its role in hematopoietic cell repopulation under the stress condition of bone marrow transplantation.

CD28 down-regulation on CD4 T cells is a marker for graft dysfunction in lung transplant recipients.

Rationale: Repeated antigen-driven proliferations cause CD28 on T cells to down-regulate. We hypothesized that alloantigen-induced proliferations could cause CD28 down-regulation in lung transplant recipients.

Objectives: To ascertain if CD28 down-regulation on CD4 T cells associated with manifestations of allograft dysfunction in lung transplant recipients.

Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer.

Since the creation of Dolly via somatic cell nuclear transfer (SCNT), more than a dozen species of mammals have been cloned using this technology. One hypothesis for the limited success of cloning via SCNT (1%-5%) is that the clones are likely to be derived from adult stem cells. Support for this hypothesis comes from the findings that the reproductive cloning efficiency for embryonic stem cells is five to ten times higher than that for somatic cells as donors and that cloned pups cannot be produced directly from cloned embryos derived from differentiated B and T cells or neuronal cells.