Aqueous Extract of Murray Attenuates Neuroinflammation in C57BL/6J Mice Induced by High-Fat and High-Fructose Diet Through Regulating Gut Microbiota and Bile Acid Metabolism.

The aqueous extract of Murray (LRE) could attenuate neuroinflammation in mice induced by a high-fat and high-fructose diet (HFFD). Moreover, LRE could adjust bile acid (BA) metabolism and the gut microbiota. Behavioral tests revealed that LRE prevented HFFD-induced cognitive deficits.

A Novel Modified ZIF-8 Nanoparticle with Enhanced Interfacial Compatibility and Pervaporation Performance in a Mixed Matrix Membrane for De-Alcoholization in Low-Concentration Solutions.

This study investigated the enhancement in bioethanol recovery from mixed matrix membranes (MMMs) by functionalizing zeolite framework-8 (ZIF-8) with imidazolate. This study focused on the separation of ethanol from low-concentration ethanol/water mixtures (typical post-fermentation concentrations of 5-10 wt%). Specifically, ZIF-8 was modified by the shell-ligand exchange reaction (SLER) with 5,6-dimethylbenzimidazole (DMBIM), resulting in ZIF-8-DMBIM particles with improved hydrophobicity, organophilicity, larger size, and adjustable pore size.

Water extract of goji berries improves neuroinflammation induced by a high-fat and high-fructose diet based on the bile acid-mediated gut-brain axis pathway.

The high-fat and high-fructose diet (HFFD) is a common diet in westernized societies, which worsens disturbances in gut microbiota and bile acid (BA) metabolism. Herein, the present study aimed to investigate the effects of the water extract of fruits (LBE) on gut microbiota and BA metabolism in mice with HFFD-induced neuroinflammation. The results showed that supplementation of LBE for 14 weeks remarkably ameliorated weight gain and insulin resistance and suppressed microglial activation and neural neuroinflammation induced by HFFD.

The polysaccharides from Auricularia auricula alleviate non-alcoholic fatty liver disease via modulating gut microbiota and bile acids metabolism.

The polysaccharides from Auricularia auricula (AAPs), containing a large number of O-acetyl groups that are related to the physiological and biological properties, seem to be potential prebiotics like other edible fungus polysaccharides. In the present study, therefore, the alleviating effects of AAPs and deacetylated AAPs (DAAPs, prepared from AAPs by alkaline treatment) on nonalcoholic fatty liver disease (NAFLD) induced by high-fat and high-cholesterol diet combined with carbon tetrachloride were investigated. The results revealed that both AAPs and DAAPs could effectively relieve liver injury, inflammation and fibrosis, and maintain intestinal barrier function.

Lonicera japonica polysaccharides alleviate D-galactose-induced oxidative stress and restore gut microbiota in ICR mice.

Lonicera japonica polysaccharides (LJPs) exhibit anti-aging effect in nematodes. Here, we further studied the function of LJPs on aging-related disorders in D-galactose (D-gal)-induced ICR mice. Four groups of mice including the control group, the D-gal-treated group, the intervening groups with low and high dose of LJPs (50 and 100 mg/kg/day) were raised for 8 weeks.

Lonicera japonica polysaccharides improve longevity and fitness of Caenorhabditis elegans by activating DAF-16.

Polysaccharide is one of the main active ingredients in Lonicera japonica Thunb. (L. japonica).

An automatic evaluation method for retinal image registration based on similar vessel structure matching.

Registration of retinal images is significant for clinical diagnosis. Numerous methods have been proposed to evaluate registration performance. The available evaluation methods can work well in normal image pairs, but fair evaluation cannot be obtained for image pairs with anatomical changes.