Publications by authors named "Yifan Lang"

Article Synopsis
  • TongFengTangSan (TFTS) is a Tibetan herbal remedy effectively used to lower uric acid levels in gout patients, but its specific mechanisms and key active components remain unclear.
  • The study used a hyperuricemia model to evaluate the efficacy of different TFTS fractions by measuring various indicators like serum uric acid and inflammatory markers, employing metabolomics techniques for deeper analysis.
  • Results showed that the CF fraction significantly reduced uric acid and regulated metabolic pathways related to purine metabolism, with CF60 identified as the main active fraction responsible for these effects.
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Paclitaxel (PTX) has been the first-line treatment for lung cancer; however, its clinical use is limited due to multidrug resistance (MDR) and adverse effects. Thus, there is an urgent need to explore agents that can enhance the anticancer efficacy of PTX by reducing drug resistance and adverse reactions. Jiegeng decoction (JG) was used as the meridian guide drug and adjuvant drug in treatment of lung cancer.

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Objective: To develop an indirect competitive chemiluminescent enzyme immunoassay( CLEIA) for the detection of bisphenol A in milk samples.

Methods: The CLEIA conditions including antigen coated concentration, concentration of methanol, concentration of enzyme labeled anti-antibody, p H and ionic strength were optimized to build competitive inhibition curve, determine the linear range and detection limit, and study the recovery of spiked milk samples.

Results: In the standard curve of the optimized CLEIA, the half maximal inhibitory concentration( IC_(50)) was 3.

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