miR-210-5p Promotes Pulmonary Hypertension by Blocking ATP2A2.

Aim: Aberrant expression of ATPase sarcoplasmic/endoplasmic retic Ca transporting 2 (ATP2A2) has attracted attention for its pathophysiologic role in pulmonary hypertension (PH). Several miRNAs, including miR-210-5p, have also been reported to be pathogenic factors in PH, but their exact mechanisms remain unknown. This study aimed to elucidate the potential mechanisms of miR-210-5p and ATP2A2 in MCT-induced PH.