Publications by authors named "Yichuan Xv"
Article Synopsis
- The study investigates how certain genes related to neutrophil extracellular traps (NETs) may contribute to the inflammation seen in ulcerative colitis (UC).
- Researchers used advanced statistical methods on data from large genetic studies to determine the relationship between NET-related genes and UC.
- Seven specific genes were identified, showing varying effects on UC risk, with CXCR1 and CXCR2 notably influencing the processes that lead to inflammation and NET formation in colon tissue.*
Background: Numerous studies have established that alterations in the gut microbiota (GM) constitute an embedded mechanism in functional dyspepsia (FD). However, the specific GM taxa implicated in the pathological process of FD have remained unclear.
Methods: A two-sample Mendelian randomization analysis was initially conducted to examine the causal relationships between GM and FD, utilizing GWAS data from the MiBioGen Consortium (18,340 cases) and FinnGenn (8,875 cases vs.