Publications by authors named "Yicheng Liu"

Background: Smartphone-based technology has been used to enhance the delivery of health care services to the public in numerous countries.

Objective: This study aims to investigate the application of patient-centric mobile medical services accessed through smartphones in the top 100 Chinese public hospitals.

Methods: Data on 124 tertiary public hospitals, ranked among the top 100 by the China Hospital Science and Technology Evaluation Metrics of the Chinese Academy of Medical Sciences (2019) and China's Hospital Rankings of the Hospital Management Institute of Fudan University (2019), were collected from the WeChat platform (Tencent Inc), mobile phone apps, and official websites until February 10, 2021.

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Background: Plasma cell dyscrasias encompass a diverse set of disorders, where early and precise diagnosis is essential for optimizing patient outcomes. Despite advancements, current diagnostic methodologies remain underutilized in applying artificial intelligence (AI) to routine laboratory data. This study seeks to construct an AI-driven model leveraging standard laboratory parameters to enhance diagnostic accuracy and classification efficiency in plasma cell dyscrasias.

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The association between anal fistula patients and colorectal cancer, as well as the potential pathophysiological mechanisms, remains unclear. To explore the relationship between anal fistula and colorectal cancer and its potential mechanisms. Analysis of GEO and TCGA databases.

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Background: Significant evidence has been documented regarding the intricate connection between the development of anal fistula (AF) and the composition of Body Mass Index (BMI). Nevertheless, due to the inherent limitations of reverse causality and confounders inherent in observational studies, this relationship remains unclarified. Our study aims to reveal the causal impact between BMI and AF, as well as identify its associated risk factors, thereby providing a more comprehensive understanding of this complex interaction.

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Article Synopsis
  • - The study explores the prevalence and risk factors of postoperative delirium in cancer patients undergoing free flap reconstruction surgery, highlighting its impact on surgical outcomes.
  • - Researchers analyzed 12 case-control studies involving over 3,200 patients, identifying significant risk factors such as age, gender, neoplasm staging, and use of certain medications, alongside protective factors like early neoplasm stage.
  • - The findings categorize risk factors into preoperative, intraoperative, and postoperative groups, aiming to inform proactive measures for preventing postoperative delirium.
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Nowadays, medical polyurethanes with favorable and durable antibacterial properties received more attention, because of avoiding repeated replacement of interventional materials and reducing patients' pain. In this thesis, non-soluble antibacterial polyurethane (NAPU) based on cation antibacterial mechanism was prepared by photo-grafting chitosan azide and heparin azide into polyurethane (PU). -NHof chitosan azide absorbed bacteria, inhibiting and breaking their mobility and structures.

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  • - The study aimed to assess the prevalence and incidence of rare diseases in China by analyzing existing epidemiological data from various databases and guidelines between 2010 and 2023.
  • - Researchers collected 1,264 data points from 277 sources, covering 110 rare diseases and 32 regions, highlighting that significant incidence or prevalence data was missing for places like Tibet and Macao.
  • - Findings reveal that eight rare diseases had high incidence rates (over 1,000 patients per million) and emphasize the need for ongoing research and medical support for those affected by these conditions.
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Cardiovascular diseases (CVDs) are currently the leading cause of death worldwide. In 2022, the CVDs contributed to 19.8 million deaths globally, accounting for one-third of all global deaths.

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It is challenging to detect and differentiate multiple diseases with high complexity/similarity from the same organ. Metabolic analysis based on nanomatrix-assisted laser desorption/ionization mass spectrometry (NMALDI-MS) is a promising platform for disease diagnosis, while the enhanced property of its core nanomatrix materials has plenty of room for improvement. Herein, a multidimensional interactive cascade nanochip composed of iron oxide nanoparticles (FeNPs)/MXene/gold nanoparticles (AuNPs), IMG, is reported for serum metabolic profiling to achieve high-throughput detection of multiple liver diseases.

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Identifying pathogenic variants from the vast majority of nucleotide variation remains a challenge. We present a method named Multimodal Annotation Generated Pathogenic Impact Evaluator (MAGPIE) that predicts the pathogenicity of multi-type variants. MAGPIE uses the ClinVar dataset for training and demonstrates superior performance in both the independent test set and multiple orthogonal validation datasets, accurately predicting variant pathogenicity.

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Overcoming the vaginal barrier to achieve sufficient drug penetration and retention is a huge obstacle for drug delivery in chemotherapeutics for cervical cancer. In this study, we investigate the feasibility of a novel composite nanocrystal/nanofiber system for improving the transmucus penetration and, thus, enhancing retention and drug delivery to the lesion of a cervicovaginal tumor. Herein, paclitaxel (PTX) was sequentially formulated in the form of nanocrystals, coated with polydopamine (PDA), and modified with PEG.

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  • - This research explored how 3D printing technology is enhancing autologous costal cartilage ear reconstruction by offering benefits in customization, efficiency, and applications in education and surgical planning.
  • - A detailed review of 283 articles identified 24 for qualitative analysis, assessing the manufacturing process and interventions using the Cochrane risk of bias tool and Newcastle-Ottawa scale for quality evaluation.
  • - While the study highlights the growing use of 3D printing in surgery, it also notes a lack of solid evidence comparing it to traditional methods due to limited high-quality studies and subjective evaluation criteria.
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Efficient thermal management is critical to ensure the safe and reliable operation of lithium-ion batteries (LIBs) as they are highly sensitive to temperature changes. Meanwhile, LIBs are exposed to various external forces during operation, such as vibration, shock, and oscillation, which may disrupt the physical and chemical processes inside the battery and lead to a decreased performance and shortened life. Here, we designed a phase change hydrogel (PCH) pad based on the polyurethane (PU) foam skeleton and demonstrated its effectiveness in efficient thermal management and improving antivibration performance.

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  • Researchers identified 96 potential oxidoreductase genes in linaridin biosynthetic gene clusters (BGCs) and successfully expressed two of these BGCs to create three new linaridins: yunnanaridins A-C.
  • Yunnanaridin A is a new addition to the type-B linaridins, while yunnanaridins B and C are the first from the type-C category, indicating a broader structural variety of linaridins and suggesting that the LinC genes may not play a role in their synthesis.
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Background: There is a lack of convenient and accurate objective methods to evaluate the clinical efficacy of thigh liposuction.

Methods: This retrospective study involved the 3-dimensional images of 19 patients who underwent bilateral thigh liposuction. Data such as volume change and volume change rate before and after surgery, circumference change, and circumference change rate of 3 planes (upper, middle, and lower) were analyzed.

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Article Synopsis
  • - The article addresses the challenges of missing views and labels in multi-view multi-label classification, a complex area in machine learning that has received limited attention.
  • - It introduces a new learning network that includes four key components: feature extraction, representation fusion, classification, and decoding, which work together to effectively manage incomplete data issues.
  • - The proposed method shows improved classification performance through both supervised and semi-supervised training, demonstrating its adaptability and effectiveness on benchmark datasets.
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Objectives: In the field of orthopedics, osteonecrosis of the femoral head (ONFH) is a common and refractory condition sometimes known as "immortal cancer" due to its complicated etiology, difficult treatment, and high disability rate. This paper's main goal is to examine the most recent literature on the pro-apoptotic effects of traditional Chinese medicine TCM monomers or compounds on osteocytes and to provide a summary of the potential signal routes.

Methods: The last ten years' worth of literature on ONFH as well as the anti-ONFH effects of aqueous extracts and monomers from traditional Chinese medicine were compiled.

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High-resolution image transmission is required in safety helmet detection problems in the construction industry, which makes it difficult for existing image detection methods to achieve high-speed detection. To overcome this problem, a novel super-resolution (SR) reconstruction module is designed to improve the resolution of images before the detection module. In the super-resolution reconstruction module, the multichannel attention mechanism module is used to improve the breadth of feature capture.

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  • Heart failure (HF) and chronic obstructive pulmonary disease (COPD) share significant clinical links, and this study explored their common genetic traits and molecular mechanisms.
  • Researchers analyzed gene expression data and identified common differentially expressed genes (DEGs), focusing on the importance of extracellular matrix and ribosomal pathways in both conditions.
  • The study also revealed connections to immune infiltration, particularly involving macrophages, and identified 4 transcription factors and 1408 microRNAs associated with both diseases, suggesting that salbutamol could have a beneficial effect.
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This brief presents the finite-time stabilization and fixed-time stabilization of multiple memristor-based neural networks (MMNNs) with nonlinear coupling. Under the retarded memristive theory, the generalized Lyapunov functional method, extended Filippov-framework and Laplacian matrix theory, we can realize both the finite-time stabilization and fixed-time stabilization problem of MMNNs by designing novel state-feedback controller and the corresponding adaptive controller with regulate parameters. Moreover, we assess the bounds of settling time for the both two kinds of stabilization respectively, and we deeply analyze the influence of initial desiring values and the linear growth condition of the controller on the system.

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The pandemic has impacted various industries, including the sports industry. However, corporate social responsibility (CSR) can mitigate the adverse effects of the crisis and promote the sports industry. To analyze the effect of CSR, the study examined the impact of perceived corporate social responsibility on injury prevention expectation, injury risk perception, and health up-gradation with the mediation of sports safety measures.

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Aqueous-phase oxygen evolution reaction (OER) is the bottleneck of water splitting. The formation of the O-O bond involves the generation of paramagnetic oxygen molecules from the diamagnetic hydroxides. The spin configurations might play an important role in aqueous-phase molecular electrocatalysis.

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Lower limb ankle exoskeletons have been used to improve walking efficiency and assist the elderly and patients with motor dysfunction in daily activities or rehabilitation training, while the assistance patterns may influence the wearer's lower limb muscle activities and coordination patterns. In this paper, we aim to evaluate the effects of different ankle exoskeleton assistance patterns on wearer's lower limb muscle activities and coordination patterns. A tethered ankle exoskeleton with nine assistance patterns that combined with differenet actuation timing values and torque magnitude levels was used to assist human walking.

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