Mutual regulation between histone methyltransferase Suv39h1 and the Wnt/β-catenin signaling pathway promoted cell proliferation and inhibited apoptosis in bone marrow mesenchymal stem cells exposed to hydroquinone.

Hydroquinone (HQ), a metabolite of benzene, is frequently utilized as a surrogate for benzene in in vitro studies and is associated with the development of acute myeloid leukemia (AML). In the hemotoxicity caused by benzene and HQ, cell apoptosis plays a key role. However, the molecular mechanisms underlying HQ are unknown.

Self-Assembled Tetraphenylethene-Based Nanoaggregates with Tunable Electrochemiluminescence for the Ultrasensitive Detection of .

As an effective ECL emitter, tetraphenylethene (TPE)-based molecules have recently been reported with aggregation-induced electrochemiluminescence (AIECL) property, while it is still a big challenge to control its aggregation states and obtain uniform aggregates with intense ECL emission. In this study, we develop three TPE derivatives carrying a pyridinium group, an alkyl chain, and a quaternary ammonium group via the Menschutkin reaction. The resulting molecules exhibit significantly red-shifted FL and enhanced ECL emissions due to the tunable reduction of the energy gap between the highest occupied molecular orbitals (HOMOs) and the lowest unoccupied molecular orbitals (LUMOs).

Specific analysis of PM-attributed disease burden in typical areas of Northwest China.

Background: Frequent air pollution events in Northwest China pose a serious threat to human health. However, there is a lack of specific differences assessment in PM-related disease burden. Therefore, we aimed to estimate the PM-related premature deaths and health economic losses in this typical northwest region, taking into account disease-specific, age-specific, and region-specific factors.

Household CO Emissions: Current Status and Future Perspectives.

The household sector, which plays a critical role in emission reduction, is a main source of greenhouse gas (GHG) emissions. Although numerous academic journals have published papers on household CO emissions (HCEs), great challenges remain in research on assessments, determinants, and further research prospects. This work reviews and projects HCEs using a bibliometric analysis and a systematic review based on the data from the Web of Science (WOS) platform from 1991 to 2020.

Health and Economic Loss Assessment of PM Pollution during 2015-2017 in Gansu Province, China.

Many studies have reported that air pollution, especially fine particulate matter (PM), has a significant impact on health and causes economic loss. Gansu Province is in the northwest of China, which is a typical economically underdeveloped area. However, few studies have evaluated the economic loss of PM related to health effects in this province.