Effects of microplastics on 3,5-dichloroaniline adsorption, degradation, bioaccumulation and phytotoxicity in soil-chive systems.

Microplastics (MPs) and pesticides are two pollutants of concern in agricultural soils. 3,5-dichloroaniline (3,5-DCA), a highly toxic metabolite of dicarboximide fungicides, commonly co-exists with MPs and poses a risk to the environment and food safety. Batch adsorption and soil incubation experiments were employed to investigate the effects of polyethylene (PE) and polylactic acid (PLA) MPs on the environmental behavior of 3,5-DCA in soil.

Percutaneous Endoscopic Lumbar Discectomy Combined with Annular Suture: Technical Video.

In this study, we introduce a technique that combines percutaneous endoscopic lumbar discectomy (PELD) with annular suture, aiming to reduce postoperative recurrence rates and enhance clinical outcomes for patients. The repair of the annulus fibrosus plays a pivotal role in healing ruptured scars, reducing the rate of nuclear reherniation, and enhancing the hardness of scar tissue through surgical intervention. Younger patients, with their higher water content in the intervertebral discs and stronger nucleus pulposus tissue, are more suitable candidates for tissue suturing, thus achieving a higher success rate.

Clinical Efficacy of Unilateral Biportal Endoscopy with Unilateral Laminotomy for Bilateral Decompression.

Unilateral biportal endoscopy (UBE) with unilateral laminotomy for bilateral decompression (ULBD) is an essential neurosurgical procedure for the treatment of lumbar spinal stenosis. This technique offers significant advantages over traditional full laminectomy and spinal fusion fixation, providing surgeons with greater operational freedom and precision in decompression. The UBE-ULBD procedure stands out because of its distinct working and observation channels, which significantly augment the surgeon's maneuverability.

Clinical Efficacy of Unilateral Biportal Endoscopic Transforaminal Lumbar Interbody Fusion.

Unilateral biportal endoscopic transforaminal lumbar interbody fusion (UBE-TLIF) is an advanced, minimally invasive spinal surgical technique characterized by the use of 2 discrete portals-one for clear visualization and continuous irrigation and the other for the dexterous manipulation of surgical instruments. This configuration not only affords an expanded view (0° or 30°) but also enhances the freedom of movement for instruments, thereby augmenting the precision and flexibility of the surgery. The superiority of UBE-TLIF lies in its capacity to facilitate rapid postoperative recovery with minimal trauma, reduced intraoperative bleeding, abbreviated hospital stays, and significant amelioration of postoperative lower back pain.

Unveiling responses and mechanisms of spice crop chive exposure to three typical pesticides using metabolomics combined with transcriptomics, physiology and biochemistry.

Pesticides are frequently used to control target pests in the production of spice crops such as chives (Allium ascalonicum). However, little information is available on the responses and underlying mechanisms of pesticide exposure in this crop. Our findings revealed that the uptake, transportation, and subcellular distribution of three typical pesticides-the fungicide pyraclostrobin (PAL), insecticide acetamiprid (ATP), and herbicide pendimethalin (PND) in chives, as well as their physiological, biochemical, metabolic, and transcriptomic responses-were dependent on pesticide properties, especially hydrophobicity.

Harnessing the capabilities of VCSELs: unlocking the potential for advanced integrated photonic devices and systems.

Vertical cavity surface emitting lasers (VCSELs) have emerged as a versatile and promising platform for developing advanced integrated photonic devices and systems due to their low power consumption, high modulation bandwidth, small footprint, excellent scalability, and compatibility with monolithic integration. By combining these unique capabilities of VCSELs with the functionalities offered by micro/nano optical structures (e.g.

Neuraminidase-1 (NEU1): Biological Roles and Therapeutic Relevance in Human Disease.

Neuraminidases catalyze the desialylation of cell-surface glycoconjugates and play crucial roles in the development and function of tissues and organs. In both physiological and pathophysiological contexts, neuraminidases mediate diverse biological activities via the catalytic hydrolysis of terminal neuraminic, or sialic acid residues in glycolipid and glycoprotein substrates. The selective modulation of neuraminidase activity constitutes a promising strategy for treating a broad spectrum of human pathologies, including sialidosis and galactosialidosis, neurodegenerative disorders, cancer, cardiovascular diseases, diabetes, and pulmonary disorders.

Multimodal Artificial Synapses for Neuromorphic Application.

The rapid development of neuromorphic computing has led to widespread investigation of artificial synapses. These synapses can perform parallel in-memory computing functions while transmitting signals, enabling low-energy and fast artificial intelligence. Robots are the most ideal endpoint for the application of artificial intelligence.

Silane modified CrO/polyimide nanocomposite films with excellent surface insulation performance for space applications.

The exploration of deep space significantly increases the probability of spacecraft failures due to surface electrostatic discharge, which imposes higher vacuum insulation protection requirements on polyimide (PI), the external insulation material of spacecrafts. To address this challenge, this study proposes using silane coupling agent KH550 for organic grafting treatment of CrOnanoparticles, which are then used to dope and modify PI to enhance the vacuum surface insulation of PI films. The KH550 grafting improves the interface strength between the fillers and the matrix, allowing the fillers to be uniformly dispersed in the matrix.

The Clinical Efficacy of Anterior Cervical Discectomy and Fusion Under Three-Dimensional Microscopy.

A plethora of studies has substantiated the remarkable clinical efficacy of anterior cervical discectomy and fusion (ACDF) in the treatment of cervical spondylotic myelopathy. This procedure effectively removes the posterior osteophytes and protruding nucleus pulposus, achieving direct decompression of the spinal cord and effectively alleviating compression symptoms. Concurrently, by distracting the intervertebral space, ACDF contributes to the restoration of the physiological curvature of the cervical spine.

Chip-scale integrated holographic devices based on top-emitting vertical cavity surface emitting lasers.

Holography technology is considered the ultimate three-dimensional (3D) visualization technology in the future. However, conventional methods for achieving holography generally utilize discrete optical components and off-chip laser sources, resulting in a large size and high complexity, which are undesirable for practical applications. In this Letter, chip-scale integrated holographic devices are realized by integrating top-emitting vertical cavity surface emitting lasers (VCSELs) with micro holograms printed by 3D femtosecond laser nanoprinting technology.

Body mass index mediates the association between four dietary indices and phenotypic age acceleration in adults: a cross-sectional study.

: Diet and body mass index (BMI) are widely recognized as being closely associated with aging. However, it remains unclear which dietary indices are associated with aging, and the extent to which BMI mediates the relationship between diet and aging. Therefore, this study investigates the mediating role of BMI in the association between various dietary indices and phenotypic age acceleration (PhenoAgeAccel).

BMSC‑derived exosome‑mediated miR‑25‑3p delivery protects against myocardial ischemia/reperfusion injury by constraining M1‑like macrophage polarization.

Myocardial ischemia/reperfusion injury (MIRI) is a significant challenge in the management of myocardial ischemic disease. Extensive evidence suggests that the macrophage‑mediated inflammatory response may play a vital role in MIRI. Mesenchymal stem cells and, in particular, exosomes derived from these cells, may be key mediators of myocardial injury and repair.

The association between multiple trajectories of macronutrient intake and the risk of new-onset diabetes in Chinese adults.

Background: The association between macronutrient intake and diabetes is unclear. We used data from the China Health and Nutrition Survey to explore the association between macronutrient intake trajectories and diabetes risk in this study.

Methods: We included 6755 participants who did not have diabetes at baseline and participated in at least three surveys.

DengueSeq: a pan-serotype whole genome amplicon sequencing protocol for dengue virus.

Background: The increasing burden of dengue virus on public health due to more explosive and frequent outbreaks highlights the need for improved surveillance and control. Genomic surveillance of dengue virus not only provides important insights into the emergence and spread of genetically diverse serotypes and genotypes, but it is also critical to monitor the effectiveness of newly implemented control strategies. Here, we present DengueSeq, an amplicon sequencing protocol, which enables whole-genome sequencing of all four dengue virus serotypes.

The association between oxidative balance score and frailty in adults across a wide age spectrum: NHANES 2007-2018.

: Frailty has been one of the most serious global public health challenges we will ever face. Oxidative stress is associated with the pathogenesis of frailty, and may be accurately reflected by the oxidative balance score (OBS). However, there have been no studies examining the effect of OBS on frailty.

Association of Physical Activity with Phenotypic Age among Populations with Different Breakfast Habits.

Background: The global aging situation has reached a serious stage, and healthy lifestyles, like regular physical activity and eating breakfast, could slow the process. Phenotypic age (PhenoAge) is regarded as a novel measure of aging. Therefore, our study aimed to quantify the impact of physical activity and eating breakfast on aging via PhenoAge and phenotypic age acceleration (PhenoAgeAccel).

The association between vitamin K intake and dyslipidemia in US adults: the mediating effect of insulin resistance.

: Dyslipidemia is one of the most common chronic diseases, and is associated with insulin resistance (IR) and inadequate vitamin K intake. We aimed to explore the association between IR, vitamin K intake, and dyslipidemia, and further to explore the mediating role of IR. : 12 860 participants from the National Health and Nutrition Examination Survey (NHANES) from 2001 to 2018 were included in this study.

Pharmacological Activation of AMPK Prevents Drp1-mediated Mitochondrial Fission and Alleviates Hepatic Steatosis .

Background: The incidence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide. Adenosine monophosphate-activated protein kinase (AMPK) activation is beneficial for NAFLD treatment. Recent studies show the excessive fission of mitochondria during NAFLD progression, so targeting mitochondria dynamics may be a possible target for NAFLD.