Therapeutic and toxicological assessment of hydroethanolic leaf extracts of in apparently healthy rats.

Unlabelled: The use of medicinal plants in the management or prevention of diseases is one of the oldest human medicinal practices worldwide. and are widely reported for their use in the management of blood disorders, hypertension, and diabetes.

Objective: The study aimed at evaluating the effects of hydroethanolic leaf extracts of and on the biochemical, hematological, and histological parameters of apparently healthy rats.

Telfairia occidentalis (Cucurbitaceae) pulp extract mitigates rifampicin-isoniazid-induced hepatotoxicity in an in vivo rat model of oxidative stress.

Objective: Drug-induced liver injury complicates antituberculosis drug treatment and is a leading cause of death worldwide. The aim of this study is to establish the ethnomedicinal claim of hepatoprotective effects of fruit pulp extract of Telfairia occidentalis against rifampicin (RIF) and isoniazid (INH)-induced oxidative stress in rats.

Methods: T.