Publications by authors named "Yiao Liu"
Ischemic stroke is a significant burden on human health worldwide. Carotid Atherosclerosis stenosis plays an important role in the comprehensive assessment and prevention of ischemic stroke patients. High-resolution vessel wall magnetic resonance imaging has emerged as a successful technique for assessing carotid atherosclerosis stenosis.
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- Intracranial atherosclerotic stenosis (ICAS) is a key factor in ischemic strokes, and this study examines how high-resolution vessel wall imaging (HR-VWI), hemodynamics, and blood inflammation relate to symptomatic ICAS (sICAS).
- Researchers analyzed data from 32 patients with middle cerebral artery stenosis by examining plaque characteristics, blood flow dynamics, and inflammatory markers to uncover correlations and predictors of sICAS.
- Findings showed that plaque enhancement and a measure called wall shear stress ratio (WSSR) are closely linked to sICAS, with WSSR identified as a significant independent risk factor.
Article Synopsis
- Intracranial atherosclerotic stenosis (ICAS) significantly contributes to ischemic strokes, and this study explores how high-resolution vessel wall imaging (HR-VWI) can evaluate the characteristics of ICAS plaques.
- The research involved analyzing data from 91 adult patients with ICAS to measure plaque enhancement and its relationship to factors like plaque burden and symptomatic status.
- Results indicated that greater plaque burden correlated with increased enhancement of plaques, and both plaque characteristics were linked to symptomatic ICAS, with plaque enhancement identified as a key independent risk factor.
17β-hydroxysteroid dehydrogenase-13 is a hepatocyte-specific, lipid droplet-associated protein. A common loss-of-function variant of HSD17B13 (rs72613567: TA) protects patients against non-alcoholic fatty liver disease with underlying mechanism incompletely understood. In the present study, we identify the serine 33 of 17β-HSD13 as an evolutionally conserved PKA target site and its phosphorylation facilitates lipolysis by promoting its interaction with ATGL on lipid droplets.
View Article and Find Full Text PDFZinc transporter 8 (ZnT8) is an important zinc transporter highly expressed in pancreatic islets. Deficiency of ZnT8 leads to a marked decrease in islet zinc, which is thought to prevent liver diseases associated with oxidative stress. Herein, we aimed to investigate whether loss of islet zinc affects the antioxidant capacity of the liver and acute drug-induced liver injury.
View Article and Find Full Text PDFSoft soil improvement is an important subject in civil engineering, and searching for an effective admixture is an important research. Silica fume (SF) is a kind of recycled material, it can be used in engineering as a pozzolanic material. The main objective of this study is to assess the effectiveness of industrial waste silica fume (SF) as an admixture to improve the cement stabilized soft soil.
View Article and Find Full Text PDF17β-Hydroxysteroid dehydrogenases (HSD17Bs) comprise a large family of 15 members that are mainly involved in sex hormone metabolism. Some HSD17Bs enzymes also play key roles in cholesterol and fatty acid metabolism. Recent study showed that hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), an enzyme with unknown biological function, is a novel liver-specific lipid droplet (LD)-associated protein in mouse and humans.
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