Publications by authors named "YiJie Dong"

Background: For improved health outcomes, children and adolescents with cancer must maintain physical activity. Individualized physical activity prescription is an effective way to promote physical activity in this group.

Objective: We reviewed and meta-analyzed evidence on the effectiveness of individualized physical activity prescriptions for improving physical activity and other health outcomes among children and adolescents with cancer.

View Article and Find Full Text PDF

Introduction: Phytoremediation is a safe and green technology for the remediation of heavy metal pollution, a global environmental problem. Bryophytes are well known for their special physiological properties, but there is little research on the use of bryophytes for phytoremediation.

Methods: In this indoor experiment, the impacts of 40 days of Cd pollution (1 (T1), 5 (T2), 10 (T3) mg·L) on Cd absorption, growth and physiological characteristics, and phyllosphere bacterial diversity of were explored.

View Article and Find Full Text PDF

The vast potential of medical big data to enhance healthcare outcomes remains underutilized due to privacy concerns, which restrict cross-center data sharing and the construction of diverse, large-scale datasets. To address this challenge, we developed a deep generative model aimed at synthesizing medical data to overcome data sharing barriers, with a focus on breast ultrasound (US) image synthesis. Specifically, we introduce CoLDiT, a conditional latent diffusion model with a transformer backbone, to generate US images of breast lesions across various Breast Imaging Reporting and Data System (BI-RADS) categories.

View Article and Find Full Text PDF

Background: Tea plants () are widely cultivated cash crops. However, fungal diseases lead to significant reductions in both the yield and quality of tea. Therefore, searching for economical, eco-friendly, and efficient biological control measures is crucial for protecting tea plants from pathogenic fungi.

View Article and Find Full Text PDF

The safety and efficacy of the lipid nanoparticle (LNP) delivery system are crucial for the successful development of messenger RNA vaccines. We designed and synthesized a series of ketal ester lipids (KELs), featuring a biodegradable ketal moiety in the linker and ester segments in the tail. Through iterative optimization of the head and tail groups of KELs, we tuned the pKa and molecular shapes, and identified (4S)-KEL12 as a safe and efficient ionizable lipid for mRNA delivery.

View Article and Find Full Text PDF

Objectives: To assess the capabilities of large language models (LLMs), including Open AI (GPT-4.0) and Microsoft Bing (GPT-4), in generating structured reports, the Breast Imaging Reporting and Data System (BI-RADS) categories, and management recommendations from free-text breast ultrasound reports.

Materials And Methods: In this retrospective study, 100 free-text breast ultrasound reports from patients who underwent surgery between January and May 2023 were gathered.

View Article and Find Full Text PDF

This is a summary of a consensus statement on the introduction of "Ultrasound microvasculomics" produced by The Chinese Artificial Intelligence Alliance for Thyroid and Breast Ultrasound. The evaluation of microvessels is a very important part for the assessment of diseases. Super-resolution ultrasound (SRUS) microvascular imaging surpasses traditional ultrasound imaging in the morphological and functional analysis of microcirculation.

View Article and Find Full Text PDF
Article Synopsis
  • HPV 16 and 18 are linked to various cancers, and although preventative vaccines exist, there is a pressing need for therapeutic vaccines to treat existing HPV infections.
  • The study introduces a new mRNA-based therapeutic vaccine, mHTV-03E2, formulated in lipid nanoparticles, which effectively triggers strong immune responses in mice, resulting in reduced tumor growth and improved survival rates.
  • Moreover, mHTV-03E2 shows promise when used in combination with immune checkpoint inhibitors, enhancing its effectiveness in fighting cancers associated with HPV16 and HPV18 infections.
View Article and Find Full Text PDF

Purpose: The importance of structured radiology reports has been fully recognized, as they facilitate efficient data extraction and promote collaboration among healthcare professionals. Our purpose is to assess the accuracy and reproducibility of ChatGPT, a large language model, in generating structured thyroid ultrasound reports.

Methods: This is a retrospective study that includes 184 nodules in 136 thyroid ultrasound reports from 136 patients.

View Article and Find Full Text PDF

Lymphoma, the most prevalent hematologic tumor originating from the lymphatic hematopoietic system, can be accurately diagnosed using high-resolution ultrasound. Microscopic ultrasound performance enables clinicians to identify suspected tumors and subsequently obtain a definitive pathological diagnosis through puncture biopsy. However, the complex and diverse ultrasonographic manifestations of lymphoma pose challenges for accurate characterization by sonographers.

View Article and Find Full Text PDF

Rationale And Objectives: To explore and validate the clinical value of ultrasound (US) viscosity imaging in differentiating breast lesions by combining with BI-RADS, and then comparing the diagnostic performances with BI-RADS alone.

Materials And Methods: This multicenter, prospective study enrolled participants with breast lesions from June 2021 to November 2022. A development cohort (DC) and validation cohort (VC) were established.

View Article and Find Full Text PDF

Background: Benign prostatic hyperplasia (BPH) is a common condition, yet it is challenging for the average BPH patient to find credible and accurate information about BPH. Our goal is to evaluate and compare the accuracy and reproducibility of large language models (LLMs), including ChatGPT-3.5, ChatGPT-4, and the New Bing Chat in responding to a BPH frequently asked questions (FAQs) questionnaire.

View Article and Find Full Text PDF

Human papillomavirus (HPV) infections account for several human cancers. There is an urgent need to develop therapeutic vaccines for targeting preexisting high-risk HPV (such as HPV 16 and 18) infections and lesions, which are insensitive to preventative vaccines. In this study, we developed a lipid nanoparticle-formulated mRNA-based HPV therapeutic vaccine (mHTV), mHTV-02, targeting the E6/E7 of HPV16 and HPV-18.

View Article and Find Full Text PDF

Lesion segmentation in ultrasound images is an essential yet challenging step for early evaluation and diagnosis of cancers. In recent years, many automatic CNN-based methods have been proposed to assist this task. However, most modern approaches often lack capturing long-range dependencies and prior information making it difficult to identify the lesions with unfixed shapes, sizes, locations, and textures.

View Article and Find Full Text PDF

Extracellular enzymes play important roles in myxobacteria degrading macromolecules and preying on other microorganisms. Glycoside hydrolases 19 (GH19) are widely present in myxobacteria, but their evolution and biological functions have not been fully elucidated. Here we investigated the comparative secretory proteome of c25j21 in the presence of cellulose and chitin.

View Article and Find Full Text PDF

Purpose: This study aimed to compare the efficacy and safety of ultrasound-guided RFA and MWA in the treatment of unifocal PTMC.

Methods: This retrospective study included 512 patients with 512 unifocal papillary thyroid microcarcinomas (PTMCs) who underwent RFA ( = 346) and MWA ( = 166) between January 2021 and December 2021. The volumes of the ablation areas were measured during follow-up, and the volume reduction rates were evaluated.

View Article and Find Full Text PDF

Objective: This prospective observational study aimed to evaluate the efficacy of radiofrequency ablation (RFA) in treating ≤ 2 cm thyroid nodules with Bethesda IV cytology and C-TIRADS 4A categorization. Additionally, the factors influencing the completed absorption of ablation (CAA) were examined.

Methods: A total of 62 cases with 62 nodules underwent ultrasound-guided RFA and were included in the study.

View Article and Find Full Text PDF

Objectives: To determine the contribution of a modified definition of markedly hypoechoic in the differential diagnosis of thyroid nodules.

Methods: A total of 1031 thyroid nodules were included in this retrospective multicenter study. All of the nodules were examined with US before surgery.

View Article and Find Full Text PDF

Background Artificial intelligence (AI) models have improved US assessment of thyroid nodules; however, the lack of generalizability limits the application of these models. Purpose To develop AI models for segmentation and classification of thyroid nodules in US using diverse data sets from nationwide hospitals and multiple vendors, and to measure the impact of the AI models on diagnostic performance. Materials and Methods This retrospective study included consecutive patients with pathologically confirmed thyroid nodules who underwent US using equipment from 12 vendors at 208 hospitals across China from November 2017 to January 2019.

View Article and Find Full Text PDF

Soil-borne plant diseases seriously threaten the tomato industry worldwide. Currently, eco-friendly biocontrol strategies have been increasingly considered as effective approaches to control the incidence of disease. In this study, we identified bacteria that could be used as biocontrol agents to mitigate the growth and spread of the pathogens causing economically significant diseases of tomato plants, such as tomato bacterial wilt and tomato Fusarium wilt.

View Article and Find Full Text PDF
Article Synopsis
  • Tomato bacterial wilt (TBW), caused by the pathogen Ralstonia solanacearum, is a major soil-borne disease affecting tomatoes, while Myxococcus xanthus R31 shows promise as a biocontrol agent against it.
  • Researchers sequenced and assembled the complete genome of R31, revealing important extracellular proteins and conducting comparative analysis with other Myxococcus strains to understand its predatory capabilities and genome expansion.
  • The findings suggest that R31's unique genetic makeup, alongside traits typical of predatory microorganisms, may enhance its ability to combat TBW, paving the way for further genetic studies on myxobacterial predation mechanisms.
View Article and Find Full Text PDF
Article Synopsis
  • Elastography ultrasound (EUS) is an important imaging method, but it faces challenges like subjective interpretation and hardware limitations that affect the miniaturization of equipment.
  • A new deep neural network has been developed to create virtual EUS (V-EUS) from traditional B-mode images, providing a cost-effective solution.
  • Analysis of 4580 breast tumor cases shows that V-EUS performs similarly to real EUS in identifying tumors, and it improves the diagnostic accuracy of portable ultrasound devices by approximately 5%.
View Article and Find Full Text PDF

Unlabelled: Tomato yellow leaf curl virus (TYLCV) causes tremendous losses of tomato worldwide. An elicitor Hrip1, which produced by , can serve as a pathogen-associated molecular patterns (PAMPs) to trigger the immune defense response in . Here, we show that Hrip1 can be targeted to the extracellular space and significantly delayed the development of symptoms caused by TYLCV in tomato.

View Article and Find Full Text PDF

Background: Understanding the intrinsic mechanisms of bacterial competition is a fundamental question. Iron is an essential trace nutrient that bacteria compete for. The most prevalent manner for iron scavenging is through the secretion of siderophores.

View Article and Find Full Text PDF

We present a Human Artificial Intelligence Hybrid (HAIbrid) integrating framework that reweights Thyroid Imaging Reporting and Data System (TIRADS) features and the malignancy score predicted by a convolutional neural network (CNN) for nodule malignancy stratification and diagnosis. We defined extra ultrasonographical features from color Doppler images to explore malignancy-relevant features. We proposed Gated Attentional Factorization Machine (GAFM) to identify second-order interacting features trained via a 10 fold distribution-balanced stratified cross-validation scheme on ultrasound images of 3002 nodules all finally characterized by postoperative pathology (1270 malignant ones), retrospectively collected from 131 hospitals.

View Article and Find Full Text PDF