Carbon-based microwave absorption materials have garnered widespread attention as lightweight and efficient wave absorbers, emerging as a prominent focus in the field of functional materials research. In this work, FeNi nanoparticles, synthesized in situ within graphite interlayers, were employed as catalysts to grow carbon nanofibers in situ via intercalation chemical vapor deposition (CVD). We discovered that amorphous carbon nanofibers (CNFs) can exfoliate and separate highly conductive graphite nanosheets (GNS) from the interlayers.
View Article and Find Full Text PDFBackground: Acute myocardial injury is defined by elevated cardiac troponin (cTn) levels with a rising and/or falling pattern, and is associated with increased mortality risk compared to patients without myocardial injury. The role of β-blockers in patients with acute myocardial injury remains unclear.
Methods: This multicenter, retrospective cohort study used data from the Tianjin Health and Medical Data Platform to assess the impact of early β-blocker use on 1-year all-cause mortality and major adverse cardiovascular events (MACE) in acute myocardial injury patients, employing a new user and target trial emulation design.
Background: Rheumatoid arthritis (RA) is a widely prevalent rheumatic condition causing joint inflammation and damage. RNA methylation plays an important role in RA. Herein, we intended to investigate the function of methyltransferase-like 3 (METTL3) and its N6-methyladenosine (m6A) methylation regulation for ras-related C3 botulinum toxin substrate 2 (RAC2) in RA.
View Article and Find Full Text PDFChronic hepatitis B (CHB) patients receiving entecavir (ETV) treatment might develop low-level viremia (LLV), which is proven to be associated with worse clinical outcomes, such as risk of drug-related mutations, progression to cirrhosis, and even hepatocellular carcinoma. This real-world prospective study evaluated the efficacy and safety of switching from ETV to tenofovir alafenamide fumarate (TAF) in CHB patients with LLV. From August 2020 to August 2023, 351 ETV-experienced CHB patients with LLV were enrolled from eight hospitals.
View Article and Find Full Text PDFIntroduction/aims: Myasthenia Gravis (MG) is a common neuromuscular junction disorder that is primarily mediated by anti-acetylcholine receptor antibodies (AChR-Ab). However, using AChR-Ab titers to predict MG severity and improvement remains controversial. This study aims to explore the relationship between AChR-Ab titers and AChR-Ab rate of change (RR-AChR-Ab, %) and MG scores.
View Article and Find Full Text PDFThe benefits of exercise for metabolic health occur in a dose-dependent manner. However, the adverse effects of overtraining and their underlying mechanisms remain unclear. Here, we show that overtraining induces hepatic fibrosis.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
May 2025
Oral ulcers are prone to recurrence and often complicated by bacterial infections. Currently, antibiotics, glucocorticoids, and anesthetics are commonly employed in clinical practice to alleviate symptoms. However, these medications exhibit limited retention in the moist and dynamic environment of the oral cavity, and their long-term use may lead to various side effects or drug resistance.
View Article and Find Full Text PDFIn clinical practice, particularly in neurology assessments, imaging multiparametric MR images with a single-sequence scan is often limited by either insufficient imaging contrast or the constraints of accelerated imaging techniques. A novel single scan 3D imaging method, incorporating Wave-CAIPI and MULTIPLEX technologies and named WAMP, has been developed for rapid and comprehensive parametric imaging in clinical diagnostic applications. Featuring a hybrid design that includes wave encoding, the CAIPIRINHA sampling pattern, dual time of repetition (TR), dual flip angle (FA), multiecho, and optional flow modulation, the WAMP method captures information on RF B1t fields, proton density (PD), T1, susceptibility, and blood flow.
View Article and Find Full Text PDFPurpose: This study aims to develop an accurate image registration framework for personalized respiratory motion modeling.
Methods: The proposed framework incorporates longitudinal data through a two-stage transfer learning approach. In the first stage, transfer learning is employed on longitudinal data collected from the same device.
Metal-organic frameworks (MOFs) have played a pivotal role as rapid and effective luminescent sensing materials. Numerous MOFs with diverse characteristics have been meticulously designed for target analytes. Previous studies have highlighted the factors of spectral characteristics, energy levels, interaction forces, and sensor stabilities for the luminescent sensing performance in response to a specific analyte.
View Article and Find Full Text PDFDiabetes Obes Metab
March 2025
Aims: To investigate the role of chemerin reduction in mediating exercise-induced Glucagon-like peptide-1 (GLP-1) secretion and the amelioration of pancreatic β-cell function in obesity.
Materials And Methods: Obesity models were established using wild-type and chemerin systemic knockout mice, followed by 8 weeks of moderate-intensity continuous aerobic exercise training. Serum chemerin levels, GLP-1 synthesis, glucose tolerance, pancreatic β-cell function, structure, and apoptosis were assessed.
Aims: Circular RNA forkhead box O3 (circFOXO3) is crucial in regulating inflammation in lung and heart injuries. However, its role in periodontitis remains unclear. We sought to elucidate the effects of circFOXO3 on periodontitis progression and related molecular mechanisms.
View Article and Find Full Text PDFWater electrolysis is a promising path to the industrialization development of hydrogen energy. The exploitation of high-efficiency and inexpensive catalysts become important to the mass use of water decomposition. Ni-based nanomaterials have exhibited great potential for the catalysis of water splitting, which have attracted the attention of researchers around the world.
View Article and Find Full Text PDFTo clarify the characteristics of greenhouse gas emissions (CO, CH, and NO) and the comprehensive greenhouse effect from vegetable fields with different organic planting years, the differences in greenhouse gas emission flux, emission intensity (GHGI), and warming potential (GWP) and their influencing factors among vegetable fields with different organic planting years in Songhuaba, including 10 years, 6 years, 3 years, and conventional planting, were analyzed. The results showed that the CO emissions from organic planting treatments were higher than those from conventional planting, whereas the NO and CH emissions were the opposite. Compared to those from conventional planting, the CO emission fluxes and cumulative emissions from organic cultivation for 10, 6, and 3 years increased by 121.
View Article and Find Full Text PDFUnlabelled: Bone metastasis from breast cancer significantly elevates patient morbidity and mortality, making early detection crucial for improving outcomes. This study utilizes radiomics to analyze changes in the thoracic vertebral bone marrow microenvironment from chest computerized tomography (CT) images prior to bone metastasis in breast cancer, and constructs a model to predict metastasis.
Methods: This study retrospectively gathered data from breast cancer patients who were diagnosed and continuously monitored for five years from January 2013 to September 2023.
Developing portable devices with reliable and swift luminescent responses for the detection of anions and pesticide residues are extremely expected for the foods safety and sequently the public health. To reduce cost and simplify the preparation and detection process, a new highly luminescent lanthanide species, [TbL(NO)]·0.5CHCN (TbL) based on an amido-armed open chain crown ether (L) was prepared and well characterized for the assembly of hybrid film, TbL@PMMA.
View Article and Find Full Text PDFIntroduction: Imbalances in blood potassium (K) homeostasis is a significant contributor to the emergence of severe complications, especially among critically ill patients. Hypokalemia and hyperkalemia are both associated with an increased risk of adverse events. However, it is not known about the impact of blood K levels on risk of intensive care units (ICU) mortality for Acute kidney injury (AKI) combined with sepsis patients.
View Article and Find Full Text PDFHormone therapy resistance and the ensuing aggressive tumor progression present a significant clinical challenge. However, the mechanisms underlying the induction of tumor malignancy upon inhibition of steroid hormone signaling remain poorly understood. Here, we demonstrate that Drosophila malignant epithelial tumors show a similar reduction in ecdysone signaling, the main steroid hormone pathway.
View Article and Find Full Text PDFThe unprecedented rise in global ambient temperatures in the last decade has significantly impacted human health, yet how heat exposure affects the development of sarcopenia remains enigmatic. Here, we demonstrate that chronic heat exposure induces skeletal muscle volume loss, leading to muscle strength and functional decline in mice. The microbiota composition of heat-exposed mice was analyzed using 16S ribosomal DNA analysis.
View Article and Find Full Text PDFSheng Li Xue Bao
October 2024
The regulation of adipose tissue homeostasis is essential for maintaining energy and metabolism balance in the body. The peripheral nervous system plays a crucial role in this process. Previous related research primarily focused on the sympathetic nervous system and its release of norepinephrine, while recent attention has shifted to the field of adipose sensory nerves.
View Article and Find Full Text PDFCarbon fiber-reinforced composites have been widely used in the aerospace industry because of their superior comprehensive performance, including high strength, low density, fatigue resistance, long service life, etc. The interface between the fiber reinforcement and the matrix is one of the key factors that determines the performance of the composites. The construction of covalent bonding connections between the components has proven to be an effective strategy for improving the interfacial bonding strength but always reduces the toughness.
View Article and Find Full Text PDFSolar energy harvesting and storage are essential in the future mix of renewable energy technologies. Hierarchical coral-structured coatings have been shown to yield high solar absorptance in concentrating solar thermal (CST) systems. However, interfacial delamination and scalability challenges owing to material complexity pose significant hurdles for the widespread industrial adoption of these hierarchical CST coatings.
View Article and Find Full Text PDFMarine algal toxins have garnered significant attention in the research community for their unique biochemical properties and potential medical applications. These bioactive compounds, produced by microalgae, pose significant risks due to their high toxicity, yet offer promising therapeutic benefits. Despite extensive research identifying over 300 marine algal toxins, including azaspiracids, brevetoxins, cyclic imines, and yessotoxins, gaps remain in the understanding of their pharmacological potential.
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