Publications by authors named "Yi-zhen Tan"
Article Synopsis
- The paper investigates the factors affecting depressive symptoms in middle-aged and elderly individuals, focusing on demographics, socioeconomics, physical health, lifestyle, and loneliness using machine learning techniques.
- A total of 976 participants aged 50 and above contributed data and activity logs, which were analyzed to identify key predictors of depression.
- Logistic Regression was found to be the most effective model, highlighting loneliness, health indicators, activity time, and perceived income as significant predictors for depression in this age group.
Background: A nanoscale drug carrier could have a variety of therapeutic and diagnostic uses provided that the carrier is biocompatible in vivo. Carbon nano-onions (CNOs) have shown promising results as a nanocarrier for drug delivery. However, the systemic effect of CNOs in rodents is unknown.
View Article and Find Full Text PDFIn the heterobiaryl cross-coupling reaction between aryl halides (Ar-X) and -methylpyrrole (-MP) catalyzed by rhodamine 6G (Rh6G) under irradiation with visible light, a highly active and long-lived (millisecond time range) rhodamine 6G radical (Rh6G) is formed upon electron transfer from ,-diisopropylethylamine (DIPEA) to Rh6G. In this study, we utilized steady-state and time-resolved spectroscopy techniques to demonstrate the existence of another electron-transfer process occurring from the relatively electron-rich -MP to photoexcited Rh6G that was neglected in the previous reports. In this case, the radical Rh6G formed is short-lived and undergoes rapid recombination (nanosecond time-range), rendering it ineffective in reducing Ar-X to aryl radicals Ar that can subsequently be trapped by -MP.
View Article and Find Full Text PDFLive attenuated Mycobacterium bovis (M. bovis), marketed as Bacille Calmette-Guérin is the only FDA-approved vaccine against tuberculosis. The prerequisite of cold chain storage between 2 and 8 °C hinders the global vaccination effort.
View Article and Find Full Text PDF[Effects of the lipid-lowering drugs on endothelial hyperplasia in inferior vena cava grafts in dogs].
Di Yi Jun Yi Da Xue Xue Bao
January 2004
Objective: To investigate the effects of the lipid-lowering drugs in alleviating endothelial hyperplasia in the inferior vena cava (IVC) grafts in dogs.
Methods: The Dacron grafts seeded with autologous venous fragments were implanted into the IVC of 20 dogs, including 12 dogs receiving oral lipid-lowering drugs serving as the treatment group and the other 8 without medication as the control group. The levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-ch) and high-density lipoprotein cholesterol (HDL-ch) in the serum were measured regularly, and all the grafts harvested to measure the thickness of the endothelium.