[Keutel syndrome with tracheal stenosis as the major symptom: case report and literature review].

Objective: To investigate the clinical characteristics, diagnosis and therapy of Keutel syndrome, and thereby to minimize the misdiagnosis.

Method: Data of a case of Keutel syndrome diagnosed at the Provincial Hospital Affiliated to Shandong University were analyzed and related literature were reviewed.

Result: An 8-month-26-day-old boy was presented with inspiratory and expiratory stridor and wheezing after movement on lung auscultation.

[Effects of budesonide on HIF-1α and VEGF expression and airway remodeling in an asthmatic mouse model].

Objective: To study the effects of budesonide on hypoxia inducible factor 1α(HIF-1α) and vascular endothelial growth factor (VEGF) expression, angiogenesis and airway remodeling in the chronic asthmatic mouse model.

Methods: Thirty female BALB/c mice were randomly divided into normal control, asthma model and treatment groups (10 in each group).The asthmatic mouse model was established via OVA challenge test.

[Mechanism of conditioned immune response in curing bronchial asthma in mice].

Objective: To understand the mechanism of effect of conditioned immune response in curing bronchial asthma.

Methods: An experimental asthma modal was produced on healthy BALB/C mice (female, 4 - 6 weeks old) by sensitization and stimulation with ovalbumin (OV A). Totally 105 mice were divided into 7 groups randomly with 15 in each and treated differently: in group CIR(1), noise was used as conditioned stimulus (CS) and budesonide and salbutamol as unconditioned stimulus (UCS) respectively, a conditioned immune response model of mice with asthma was established by the combination of CS and UCS 7 times (7 days), then the mice were given CS only, and the combination were given once a week for 20 weeks.

[Expression of neuronal acetylcholine receptor alpha 7 (nAChRalpha7) in peripheral blood CD(4)(+) T lymphocytes from asthmatic children].

Objective: To investigate the relationship between the expression of neuronal acetylcholine receptor alpha 7 (nAChRalpha7) and the role of nAChRalpha7 in the development of asthma by detecting the expression of nAChR alpha7 on CD(4)(+) T lymphocytes in the peripheral blood and the level of cytokines IFN-gamma and IL-4 in the blood serum from children with asthma.

Methods: Thirty patients in the asthma group and 20 healthy children in the normal control group were included. Peripheral blood was collected, and the serum was harvested.

Thirty-one patients with primary hepatocellular carcinoma survived for more than 5 years after hepatectomy.

Objective: To investigate the factors affecting prognosis of patients with primary hepatocellular carcinoma (PHC) after resection.

Methods: From 1976 to 1992, 213 patients with PHC treated with hepatectomy were followed up for more than 5 years. Thirty-one of the patients who had survived for more than 5 years were compared with 56 patients who had survived for less than 5 years.