Enhance antimony adsorption from aquatic environment by microwave-assisted prepared FeO nanospherolites.

A novel hierarchically nanostructured magnetite (FeO) was manufactured using microwave-assisted reflux method without surfactants. The nanostructured FeO is formed via the co-precipitation of Fe(III) and Fe(II), followed by a nanocrystal aggregation-based mechanism. Moreover, the effects of solution pH, contact time, initial Sb concentration, coexisting anions, and recycle numbers on the adsorption of nanostructured FeO toward Sb were extensively examined in the batch adsorption tests.

[Effects of long-term straw returning on distribution of aggregates and nitrogen, phosphorus, and potassium in paddy].

In order to understand the composition and stability of soil aggregate in paddy filed, as well as the changes of soil aggregate-associated nitrogen (N), phosphorus (P) and potassium (K) after straw addition combined with chemical fertilization, soil samples were collected from a 34-year positioning experiment with three treatments, including no chemical fertilizer (CK), chemical fertilizer only (NPK), and straw addition plus chemical fertilizer (NPKS). The composition of water-stable aggregates at the soil layers of 0-20 cm and 20-40 cm were analyzed with the wet sieving method, as well as the distribution characteristics, contribution rate and activation rate of soil aggregate-associated N, P, and K. Results showed that the fractions of >2 mm and 0.

NID2 can serve as a potential prognosis prediction biomarker and promotes the invasion and migration of gastric cancer.

Background: Nidogen-2 (NID2) is a ubiquitous component in the basement membrane and plays an important role in the development of malignant tumors. However, the specific function and mechanism of the NID2 gene in gastric cancer remains unclear. In this study, we aimed to investigate the role of NID2 in gastric cancer(GC).

[Effect of BBG on Acute Graft-Versus-Host Disease in Mice after Allogeneic Hematopoietic Stem Cell Transplantation].

Objective: To investigate the effect of P2X7R antagonist brilliant blue G (BBG) on aGVDH of mice after allo-HSCT.

Methods: aGVHD mouse model after HSCT was established and treated with the P2X7R antagonist BBG of different dosages (50 mg/kg and 75 mg/kg). After treatment, the survival, body weight, pathological and liver function of aGVDH mice were abserved, and the expression levels of P2X7, NLRP3, caspase-1, IL-1β, IL-18 mRNA and protein were evaluated by real-time PCR and Western blot.

MicroRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in colorectal cancer.

Colorectal cancer (CRC) is the most common cancer diagnosed worldwide, and the development of metastases is a major cause of mortality. Accumulating evidence suggests that microRNAs are important in carcinogenesis by affecting the expression of genes that regulate cancer progression. A number of studies have shown that miR-206 is frequently downregulated in many human malignancies, including CRC, and is associated with a more malignant phenotype.

[The correlation between chemotherapeutic efficacy and breast cancer susceptibility gene 1 and class IIIβ-tubulin protein expression in non-small cell lung cancer patients].

Objective: To investigate the predictive value of breast cancer susceptibility gene 1 (BRCA1) and class IIIβ-tubulin protein expression in tumor tissue for the efficacy of taxol and cisplatin combined chemotherapy (TP) in stage IIIB/IV non-small cell lung cancer (NSCLC) patients.

Methods: A total of 92 stage IIIB/IV NSCLC patients were recruited with 87 patients evaluated. Bronchoscopy or lung puncture tumor biopsy samples were obtained with BRCA1 and class IIIβ-tubulin protein expression examined immunohistochemically before chemotherapy.

[Effects of allicin on invasion and metastasis of colon cancer LoVo cell line in vitro].

Objective: To study the effect of allicin on invasion and metastasis of human colon cancer cell line LoVo in vitro and furthermore elucidate its anticancer mechanisms.

Methods: MTT assay was used to test dynamically the effect of cell growth inhibition. The inhibitory effects of allicin on movement, adhesiveness and invasiveness of LoVo cells were evaluated by the migratory test, adhesion test and Transwell chamber experiment.

[Blocking enhancive effect of vascular endothelial growth factor on proliferation of rhabdomyosarcoma cell line RH4 by avastin].

Background & Objective: Vascular endothelial growth factor (VEGF) signal pathway is a hot spot in recent tumor research, but its role in rhabdomyosarcoma (RMS) has rarely been reported, and its mechanism is unclear. This study was to investigate the expression of VEGF and its receptors (VEGFR) in RMS cell line RH4 to reveal the mechanism of VEGF signal pathway, and explore the therapeutic value of Avastin in RMS in vitro.

Methods: Reverse transcription-polymerase chain reaction (RT-PCR) was used to detect the expression of VEGF, VEGFR1, VEGFR2, and VEGFR3 mRNA in RH4 cells.

[Feasibility of chitosan as gene therapy vehicle].

Background & Objective: Recently, chitosan, as a nonviral vehicle for transferring DNA molecules into the cells, has attracted much attention because of its cationic properties. This study was to investigate characteristics and transfection activity of chitosan-pDNA microparticles, and confirm the feasibility of chitosan as gene therapy vehicle, which may be employed in further in vivo study.

Methods: Plasmid DNAs were amplified in Eschericha Coli JM109 with transfection of enhanced green fluorescence protein (EGFP) gene, and isolated according to the protocol of Qiagen plasmid midi kit.