Risk Factors Influencing Medication-Related Osteonecrosis of the Jaws (MRONJ) Following Dental Extraction Among Osteoporotic Patients in Taiwan.

Aim: Antiresorptive therapy (ART) is commonly used in osteoporotic patients to prevent bone loss. This retrospective cohort study aimed to identify the risk factors associated with medication-related osteonecrosis of the jaw (MRONJ) in osteoporotic patients receiving dental extraction during ART.

Materials And Methods: Data were collected from 937 patients with 1067 dental extractions conducted between January 2003 and May 2022, including 519 patients on oral alendronate, 276 on denosumab, and 172 on zoledronate.

Cost-effective 3D-printed rotatable reflectors for two-dimensional beam steering.

In this paper, we have developed a 2D optical scanning module comprising cascaded 3D-printed one-axis rotating mirrors with large areas (30×30 for the X-direction scan and 60×25 for the Y-direction scan). Each mirror device contains a square or rectangular silicon substrate coated with aluminum, serving as the mirror. A 3D-printed structure, including the mirror frame (with four embedded mini permanent magnets on the backside), torsion springs, and base, is combined with the mirror; two electromagnets are situated under the mirror as the actuation mechanism.

Correction to "Gut microbiota dysbiosis in Chinese children with type 1 diabetes mellitus: An observational study".

[This corrects the article on p. 2394 in vol. 27, PMID: 34040330.

Gut microbiota dysbiosis in Chinese children with type 1 diabetes mellitus: An observational study.

Background: Gut microbiota dysbiosis is reportedly actively involved in autoimmune diseases such as type 1 diabetes mellitus (T1DM). However, the alterations in the gut microbiota and their correlation with fasting blood glucose (FBG) in Chinese children with T1DM remain unclear.

Aim: To investigate alterations in the gut microbiota in Chinese children with T1DM and their associations with clinical indicators.

A multifunctional DNA polymerase I involves in the maturation of Okazaki fragments during the lagging-strand DNA synthesis in Helicobacter pylori.

Helicobacter pylori is the most infectious human pathogen that causes gastritis, peptic ulcers and stomach cancer. H. pylori DNA polymerase I (HpPol I) is found to be essential for the viability of H.

Feasibility of measuring spleen stiffness with MR elastography and splenic volume to predict hepatic fibrosis stage.

Aim: The aim of this study was to investigate the relationship between spleen stiffness value, splenic volume and the liver fibrosis stages.

Materials And Methods: This retrospective study was approved by the institutional review board of our institute. We enrolled 109 patients that had undergone abdominal MR imaging and histopathological examination.

Comparative genomic study of three species within the genus Ornithinibacillus, reflecting the adaption to different habitats.

In the present study, we report the whole genome sequences of two species, Ornithinibacillus contaminans DSM22953(T) isolated from human blood and Ornithinibacillus californiensis DSM 16628(T) isolated from marine sediment, in genus Ornithinibacillus. Comparative genomic study of the two species was conducted together with their close relative Ornithinibacillus scapharcae TW25(T), a putative pathogenic bacteria isolated from dead ark clam. The comparisons showed O.

Targeting the vasculature of colorectal carcinoma with a fused protein of (RGD)₃-tTF.

Purpose: Truncated tissue factor (tTF) fusion protein targeting tumor vasculature can induce tumor vascular thrombosis and necrosis. Here, we generated (RGD)₃-tTF in which three arginine-glycine-aspartic (RGD) targeting integrin α(v)β₃ and tTF induce blood coagulation in tumor vessels.

Methods: The bioactivities of (RGD)₃-tTF including coagulation activity, FX activation, and binding with integrin α(v)β₃ were performed.

[Expression of OCT4 in gastric cancer cell lines and its significance].

Objective: To detect the expression of octamer-binding protein-4 (OCT4) in gastric cancer cell lines with different differentiation (MKN-28, SGC-7901, BGC-823) and normal gastric mucosal cells line GES-1, and further assess the relationship between OCT4 expression and the differentiation grade of gastric carcinoma cells.

Methods: Expression level of OCT4 in GES-1, MKN-28, SGC-7901 and BGC-823 was detected by reverse transcription-polymerase chain reaction (RT-PCR), and OCT4 siRNA was employed to interfere OCT4 expression in BGC-823 cell lines. Detect the quantity of OCT4 mRNA and OCT4 protein by fluorescent quantitative PCR and Western blot respectively.

Liquid-phase non-thermal plasma-prepared N-doped TiO(2) for azo dye degradation with the catalyst separation system by ceramic membranes.

This study strived to improve the photocatalytic activity by using liquid-phase non-thermal plasma (LPNTP) technology for preparing N-doping TiO(2) as well as to separate/recover the N-dope TiO(2) particles by using ceramic ultrafiltration membrane process. The yellow color N-doped TiO(2) photocatalysts, obtained through the LPNTP process, were characterized with UV-Vis spectroscopy, X-ray diffraction (XRD), and electron spectroscopy for chemical analysis (ESCA). The UV-Vis spectrum of N-doped TiO(2) showed that the absorption band was shifted to 439 nm and the band gap was reduced to 2.

GABAB-receptor-mediated suppression of sympathetic outflow from the spinal cord of neonatal rats.

Using a splanchnic nerve-spinal cord preparation in vitro that could spontaneously generate sympathetic nerve discharge (SND), we investigated the roles of intraspinal GABA(B) receptors in the regulation of SND. Despite an age-dependent difference in sensitivity, bath applications of baclofen (Bac; GABA(B)-receptor agonist) consistently reduced SND in a concentration-dependent manner. The drug specificity of Bac in activation of GABA(B) receptors was verified by application of its antagonist saclofen (Sac) or CGP-46381 (CGP).