[Changes of opsin expression in experimental form-deprivation and defocus myopia in guinea pig].

Objective: To investigate the opsin expression in form-deprived and defocus myopia in guinea pig and to study the relationship between the opsin expression and the experimental myopia.

Methods: Fifty guinea pigs were randomized into form-deprived group, defocus group (n = 20 in each group) and normal group (n = 10). Guinea pigs in form-deprived group wore a diffuser RGP on one eye since one week after birth.

Influence of internal optical astigmatism on the correction of myopic astigmatism by LASIK.

Purpose: To investigate the influence of the origin of astigmatism on the correction of myopic astigmatism by LASIK.

Methods: A retrospective study was conducted of the records of 192 patients (192 eyes) undergoing LASIK for correction of myopia and myopic astigmatism from January to September 2010. Ocular residual astigmatism (ORA) and lenticular astigmatism (LA) were determined by vector analysis using objective refraction and Pentacam (Oculus Optikgeräte GmbH) imaging of both corneal surfaces.

Sonic hedgehog expression and its role in form-deprivation myopia in mice.

Purpose: To investigate whether sonic hedgehog (Shh) plays a role in postnatal eye development and the development of experimentally induced myopia.

Methods: Expression of Shh, Patched-1 (Ptc-1), and Gli3 was evaluated in the eyes of 13- to 14-day-old C57B/L6 mice with form-deprivation myopia (FDM) (n = 100) and controls (n = 100) using real-time PCR and Western blot analysis. In a second experiment, 336 mice were divided into two groups: the first wore a unilateral translucent diffuser to induce myopia and the second served as a control.

[Comparison of congenital color vision deficiencies prevalence between Han and Uygur high-school students].

Objective: A population-based study was conducted to compare the prevalence of congenital color vision deficiencies (CVD) in high-school students of Uygur and Han nationalities in Xinjiang Uygur autonomous region.

Methods: Students from 7 high schools were examined with pseudoisochromatic color plates and further with Farnsworth Munsell 100 test. The chi-square test was applied to compare categorical variables, and the independent-samples t test was used to compare the measure data.

Incidence of myopia in high school students with and without red-green color vision deficiency.

Purpose: To investigate the influence of color vision on myopia development by testing refraction error and axial length of the eye for high school students with and without color vision deficiency (CVD).

Methods: A school-based cross-sectional, cluster sample study was conducted to test the color vision and refractive error of 16,539 high school students. Students were screened for CVD using a pseudoisochromatic plate.

[Clinical features of Best vitelliform macular dystrophy].

Objective: To investigate the clinical features of Best vitelliform macular dystrophy (BVMD) in Chinese patients.

Methods: Ten consecutive patients (20 eyes) were diagnosed as BVMD by the fundus photography, EOG, fluorescein angiography (FFA) and optical coherence tomography (OCT). Their clinical data were analyzed retrospectively.