Publications by authors named "Yi-qun Ma"
Article Synopsis
- The study tried to tell the difference between two medical conditions: tuberculous spondylodiscitis (TS) and pyogenic spondylodiscitis (PS) using tests and scans.
- They looked at data from 81 patients and found certain signs in tests that could help identify each condition better.
- The researchers created a new model that can predict the right diagnosis with a high accuracy of about 91.4%, which could help doctors make better decisions when treating patients.
Article Synopsis
- The study discusses the challenges in creating bone-like scaffolds for regeneration due to the unique structure and composition of natural bone.
- Researchers developed a biomimetic scaffold made from decellularized extracellular matrix and regenerated silk fibroin, enhanced with magnetic nanoparticles, showing promising properties like good cytocompatibility and increased compressive strength.
- The scaffolds, when combined with an external magnetic field, promoted cell migration and bone formation, with underlying mechanisms related to the release of calcium, indicating potential for improved bone regeneration strategies.
Chondrocyte senescence is a decisive component of age-related osteoarthritis, however, the function of small noncoding RNAs (sncRNAs) in chondrocyte senescence remains underexplored. Human hip joint cartilage chondrocytes were cultivated up to passage 4 to induce senescence. RNA samples were extracted and then analyzed using small RNA sequencing and qPCR.
View Article and Find Full Text PDFStudy Design: This is an experimental animal study.
Objective: The objective of this study was to compare an anterior cervical discectomy and interbody fusion of a novel polylactide/nano-sized β-tricalcium phosphate (PLA/nβ-TCP) bioabsorbable self-retaining cervical fusion cage (BCFC) with an autologous bone graft and polyetheretherketone (PEEK) cages.
Background: Although PLA cervical cages have potential advantages compared with traditional materials, they are not currently routinely used in spine surgery because of undesirable effects such as the lack of osteoconductivity and osteolysis around the implant.
Background: The purpose of this biomechanical in vitro study was to compare the kinematics and intradiscal pressure achieved with 2 methods: L4-L5 pedicle screw-rod fixation (PSRF) with an upper L3-L4 Coflex device and L4-L5 PSRF alone. The results were used to characterize the biomechanics of the topping-off operation with a Coflex device for the lumbar motion segment adjacent to single-level rigid fixation.
Material/methods: Six human cadaveric spine specimens were biomechanically tested in vitro (6 males, 0 females).
Decreased Zn(2+) Influx Underlies the Protective Role of Hypoxia in Rat Nucleus Pulposus Cells.
Biol Trace Elem Res
November 2015
Zn(2+) is an essential component of metalloproteinases, and is required for their activity in cartilage; however, the effect of Zn(2+) on nucleus pulposus (NP) cells has not been widely investigated. The aim of this paper was to investigate the effect of intracellular Zn(2+) concentration ([Zn(2+)]i) in hypoxia-induced regulation of metalloproteinases (MMPs) and extracellular matrix (ECM) production in NP cells. NP cells from Sprague-Dawley (SD) rats were cultured as monolayers or in alginate beads.
View Article and Find Full Text PDFObjective: To compare the safety and efficacies of traditional open versus percutaneous monosegmental pedicle screw fixation in the treatment of incomplete thoracolumbar spinal fracture.
Methods: A retrospective analysis was conducted for 44 inpatients with a diagnosis of incomplete thoracolumbar spinal fracture (AO classification: A3.1 and A3.
Objective: To investigate the safety and therapeutic effects of monosegment pedicle instrumentation in treating incomplete thoracolumbar burst fracture.
Methods: A retrospective analysis was conducted on 56 inpatients with incomplete thoracolumbar burst fracture (AO classification: A3.1 and A3.
Environmental contaminants are powerful mutagenic factors for organisms. Several testing materials and methods have been used to assess the genotoxicity of environmental factors. Transgenic plants testing system can not only evaluate the level of genotoxicity, but also provide information on the genetic effects at molecular level.
View Article and Find Full Text PDFObjective: To observe the expression of laminin and fibronectin in alkali-burned corneas in rats.
Methods: A total of 18 normal Wistar rats were randomly divided into 6 groups (n = 3 in each group). For each rat, one eye was injured by alkali burn, the other one was taken as the normal control.