Nobiletin inhibits cell growth through restraining aerobic glycolysis via PKA-CREB pathway in oral squamous cell carcinoma.

Background/aim: Nobiletin is a polymethoxylated flavone enriched in Citrus and is used as an important drug in traditional Chinese medicine for various kinds of diseases. Among its multiple functions, it has shown that nobiletin inhibits proliferation of various cancer cells. However, it is unclear whether nobiletin inhibits the growth of oral squamous cell carcinoma (OSCC) cells.

TMPyP4 promotes cancer cell migration at low doses, but induces cell death at high doses.

TMPyP4 is widely considered as a potential photosensitizer in photodynamic therapy and a G-quadruplex stabilizer for telomerase-based cancer therapeutics. However, its biological effects including a possible adverse-effect are poorly understood. In this study, whole genome RNA-seq analysis was used to explore the alteration in gene expression induced by TMPyP4.

[EMD Time-Frequency Analysis of Raman Spectrum and NIR].

This paper analyzes the Raman spectrum and Near Infrared Spectrum (NIR) with time-frequency method. The empirical mode decomposition spectrum becomes intrinsic mode functions, which the proportion calculation reveals the Raman spectral energy is uniform distributed in each component, while the NIR's low order intrinsic mode functions only undertakes fewer primary spectroscopic effective information. Both the real spectrum and numerical experiments show that the empirical mode decomposition (EMD) regard Raman spectrum as the amplitude-modulated signal, which possessed with high frequency adsorption property; and EMD regards NIR as the frequency-modulated signal, which could be preferably realized high frequency narrow-band demodulation during first-order intrinsic mode functions.

Isolated Influences of Surgery Repair on Maxillofacial Growth in Complete Unilateral Cleft Lip and Palate.

Purpose: The purpose of this study was to investigate the maxillofacial morphologic characteristics of children with complete unilateral cleft lip and palate (UCLP) with and without surgical correction and better understand the relation between surgery and inhibition of maxillary growth.

Material And Methods: Lateral cephalometric radiography was performed in 3 groups of 9-year-old children: 1) 20 whose UCLP was repaired in infancy; 2) 20 who had no surgical repair or any relevant treatments; and 3) 20 without UCLP who served as controls.

Results: Marked morphologic deviations of patients in groups 1 and 2 compared with the control group were observed in the cranial base angle, maxillary heights, length and shape of the mandible, and anteroposterior jaw relation.

Non-joint effusion is associated with osteoarthritis in temporomandibular joints with disk displacement.

Purpose: The aim of this study was to examine the possible association between different grades of joint effusion (JE) and osteoarthritis (OA) in temporomandibular joint (TMJ) anterior disk displacement without reduction (ADDwoR).

Material And Methods: A sample of 101 female patients 20-40 years of age with unilateral TMJ ADDwoR were retrospectively reviewed. JE and OA were diagnosed with magnetic resonance imaging (MRI).

[Adaptive "3R" De-Noising Algorithm Based on Near Infrared Bi-Spectrum].

Adaptive de-noising algorithm is proposed based on transmission spectrum and absorption spectrum of near infrared. Near infrared transmission spectrum and absorption spectrum collected synchronously are decomposed into intrinsic mode functions by ensemble empirical mode decomposition; the intrinsic mode function is a single frequency component. Correlations between intrinsic mode functions and transmission spectrum, absorption spectrum were calculated, and the correlation between intrinsic mode functions of transmission spectrum and absorption spectrum was also computed.

Surgical treatment of temporomandibular disorder in a 24-year-old male patient with ganglion cyst.

Ganglion cysts are common pseudocystic masses, whereas those arising from the temporomandibular joint (TMJ) are rare entities. We report a case of ganglion cyst of the right TMJ with symptomatic bilateral TMJ internal derangement in a 24-year-old man. Disk repositioning using bone anchors and excision of the ganglion cyst were performed.

[Adaptive EEMD residue related baseline correction algorithm].

Baseline correction is an important part of spectral analysis; the existing algorithms usually need to set the key parameters and does not have adaptability. The spectral baseline is fitted by the residue according to the feature of ensemble empirical mode decomposition (EEMD for short). The correlation between residual and original signal, the self-correlation and the cross-correlation of residual form the residual related rule.

Bacillus vanillea sp. nov., Isolated from the Cured Vanilla Bean.

A Gram-positive bacterium, designated strain XY18(T), was isolated from a cured vanilla bean in Hainan province, China. Cells were rod-shaped, endospore producing, and peritrichous flagella. Strain XY18(T) grew at salinities of 0-8 % (w/v) NaCl (optimally 1-4 %), pH 4.

[EEMD de-noising adaptively in Raman spectroscopy].

It is well known that the second generation wavelet is the best de-noising means, but the result of de-noising depends on how to set up the basis function, decomposition layers and threshold parameters. Without parameter setting empirical mode decomposition (EMD) decomposes the signal into intrinsic mode functions (IMF), then structuring IMF filter and the de-noising process is adaptive. It is worth noting that the signal and the noise are mixed together in very high frequency, that is to say that there has been mode overlap, and what happened will affect the de-noising effect.

A data-driven noise reduction method and its application for the enhancement of stress wave signals.

Ensemble empirical mode decomposition (EEMD) has been recently used to recover a signal from observed noisy data. Typically this is performed by partial reconstruction or thresholding operation. In this paper we describe an efficient noise reduction method.

Magnetic resonance imaging assessment of temporomandibular joint soft tissue injuries of intracapsular condylar fracture.

We evaluated the soft tissue of the temporomandibular joint (TMJ) with magnetic resonance imaging (MRI) after intracapsular condylar fracture. Eighteen consecutive patients (19 TMJ) were diagnosed between 1 January 2010 and 30 October 2011. They were examined using bilateral sagittal and coronal MRI, which were obtained immediately after injury to assess the displacement of the disc, whether there was a tear in capsule or the retrodiscal tissue, and whether there was an effusion in the joint.

Stress wave signal denoising using ensemble empirical mode decomposition and an instantaneous half period model.

Stress-wave-based techniques have been proven to be an accurate nondestructive test means for determining the quality of wood based materials and they been widely used for this purpose. However, the results are usually inconsistent, partially due to the significant difficulties in processing the nonlinear, non-stationary stress wave signals which are often corrupted by noise. In this paper, an ensemble empirical mode decomposition (EEMD) based approach with the aim of signal denoising was proposed and applied to stress wave signals.

Real time 3D simulation for nose surgery and automatic individual prosthesis design.

This paper presents an intuitive nose surgery planning and simulation system, using 3D laser scan image and lateral X-ray image, to provide high quality prediction of the postoperative appearance, and design the patient specific prosthesis model automatically. After initial registration, the internal surface of soft tissue at the nose region was generated by the statistical data for soft tissue thickness adapted by the individual thickness information from the X-ray image. Then, the sketch contour of the 3D scan data on the lateral X-ray image was modified manually or adjusted automatically according to some aesthetic statistical data, to drive the simulation in real time by the state-of-the-art Laplacian surface deformation method.

Application of MRI in indirect temporomandibular joint injury without condylar fracture.

Objective: To discuss the application of MRI in indirect temporomandibular joint injury without condylar fracture.

Methods: MRI examination on temporomandibular joint was conducted in 28 patients with indirect injury to temporomandibular joint without condylar fracture. The scanning sequence included T(1)WI, PDWI on oblique sagittal section at both open and closed mouth positions, and T(1)WI, T(2)WI on oblique coronal section.

[Establishment of a three-dimensional finite element model of mandible with dental implants for immediate loading].

Purpose: To establish a three-dimensional finite element model of mandible with dental implants for immediate loading, which will provide a basis for study of the biomechanical characteristics of the immediate loading implant-bone interface.

Methods: A female edentulous mandible was adopted for CT scanning, the scanned data were saved with the form of DICOM, and then input into compute. Universal Surgical Integration System which was developed by ourselves and ANSYS 10.

Identification and classification in le fort type fractures by using 2D and 3D computed tomography.

Objective: To evaluate the usefulness of two- dimensional (2D) and three-dimensional (3D) computed tomography (CT) in the identification and classification of Le Fort type fractures.

Methods: Sixty-two patients with different types of Le Fort fractures underwent CT scanning and 3D-CT reconstruction. The data were analyzed by multiplanar reconstruction (MPR), surface shaded display (SSD) and volume rendering (VR) respectively.

[A finite element analysis system for two-demension morphological analysis of the soft tissue in orthognathic surgery].

Objective: To evaluate a finite element method (FEM) for analysis of the cranial-facial morphology.

Methods: The two-dimensional finite element analysis system was established and used to analysis the lateral side morphology of the soft tissue by the change of each finite unit of the soft tissue in a X-ray cranial-facial lateral cepholometrics film.

Results: The finite element analysis system was showing very well in the figures and data made by the system.