Dual-polarized transmissive metasurfaces for near-unitary-NA analog spatial computing empowered by impedance matching and mismatching.

In recent years, due to the increasing requirement for real-time and massive data processing, optical analog computation has arisen as a promising alternative to digital computation. Optical spatial differentiation plays a fundamentally important role in various emerging technologies, including augmented reality, autonomous driving, and object recognition. However, previous demonstrations encountered several limitations, such as the dependence on polarization states and a typically limited numerical aperture (NA) of about 0.

A Novel Quality Control Strategy for the Preparation of High-Quality Recombinant Allergens in Escherichia coli: A Case Study of Der f 2.

Introduction: Recombinant allergens produced by Escherichia coli (E. coli) system play an important role in the component-resolved diagnostics of allergy and vaccine development. However, incorrect folding of recombinant allergens may affect their application.

[Effects of " Air Pollution Prevention and Control Action Plan " on PM and Chemical Compositions in Zhengzhou in Polluted Winters].

The Air Pollution Prevention and Control Action Plan （APPCAP） was promulgated in China in 2013. To explore the effectiveness of APPCAP on PM in winter in Zhengzhou, PM samples were collected in Zhengzhou Monitoring Center during December 2013 and December 2018. The chemical composition of PM was analyzed, including EC, OC, water soluble ions, and metal elements.

[Pollution Characteristics, Source, and Health Risk Assessment of Metal Elements in PM Between Winter and Spring in Zhengzhou].

A total of 18 metal elements in ambient PM in Zhengzhou were continuously determined using an online heavy metal observation instrument in January and April, 2021, and the changes in element concentrations were analyzed. Metal elements were traced via enrichment factors, positive matrix factorization (PMF), and a characteristic radar chart. The US EPA health risk assessment model was used to assess the health risks of heavy metals, and the backward trajectory method and the concentration-weighted trajectory (CWT) method were used to evaluate the potential source regions of health risks.

Novel plasma microRNA expression features in diagnostic use for Epstein-Barr virus-associated febrile diseases.

Background: Epstein-Barr virus (EBV) is widely infected in humans and causes various diseases. Among them, microRNAs of EBV play a key role in the progression of EBV-associated febrile diseases. There're few specific indicators for rapid differential diagnosis of various febrile diseases associated with EBV, and the lack of more reliable screening methods with high diagnostic utility has led to spaces for improvement in the accurate diagnosis and efficient treatment of relevant patients, making EBV infection a complicated clinical problem.

[Characteristics of Secondary Inorganic Ions in PM and Its Influencing Factors in Summer in Zhengzhou].

Nitrate (NO), sulfate (SO), and ammonium (NH) are important components of PM, and studying their characteristics and influencing factors is essential for the continuous improvement of air quality. A series of online instruments were used to analyze the chemical components of PM in Zhengzhou in the summer of 2020. The results showed that the average (PM) was (28 ±13) μg·m, showing a daily variation characteristic of high at night and low during the day.

Artificial intelligence-driven design of the assembled major cat allergen Fel d 1 to improve its spatial folding and IgE-reactivity.

Background: Cat-derived allergens are considered as one of the most common causes of allergic diseases worldwide. Fel d 1 is a major cat allergen and plays an important role in immunoglobulin E (IgE)-reaction diagnosis. However, the two separate chains of Fel d 1 exhibited lower IgE-reactivity than its complete molecule of an assembled form, which makes it difficult to efficiently prepare and limits the application of Fel d 1 in molecular diagnosis of cat allergy.

plays a key role in gastric adenocarcinoma induced by spasmolytic polypeptide-expressing metaplasia.

(), a group 1 human gastric carcinogen, is significantly associated with chronic gastritis, gastric mucosal atrophy, and gastric cancer. Approximately 20% of patients infected with develop precancerous lesions, among which metaplasia is the most critical. Except for intestinal metaplasia (IM), which is characterized by goblet cells appearing in the stomach glands, one type of mucous cell metaplasia, spasmolytic polypeptide-expressing metaplasia (SPEM), has attracted much attention.

[Evaluation of Changes in PM Exposure Concentration and Health Risk for Urban Resident in Zhengzhou Based on High Spatial Resolution Grids].

In recent years, complex air pollution with the characteristic pollutant of PM has remained serious in China. Long term exposure to PM might harm residential health and can increase premature death from specific diseases. The annual average concentration of PM in Zhengzhou was much higher than the national secondary standard, which has an extremely negative impact on the health of residents.

Systemic injury caused by taurocholate-induced severe acute pancreatitis in rats.

Systemic injury plays a central role in severe acute pancreatitis (SAP). Retrograde biliopancreatic duct infusion of sodium taurocholate (NaT) is commonly used to establish SAP animal models. To better characterize the systemic injury in this model, SAP was induced in Sprague-Dawley rats by NaT administration (3.

De Winter electrocardiogram pattern due to type A aortic dissection: a case report.

Background: De Winter electrocardiograph (ECG) pattern is an atypical presentation of acute myocardial infarction (AMI) due to severe stenosis of the left anterior descending (LAD). Complications of acute aortic dissection (AD) in the setting of acute myocardial infarction (AMI) with de Winter sign are relatively rare and physicians may easily miss the diagnosis of AD. We report a case of patient with acute chest pain and de Winter ECG pattern due to AD involving the left main coronary artery (LM), LAD and left circumflex artery (LCX).

[Evaluation of the Reduction in PM Concentration During the National Traditional Games of Ethnic Minorities in Zhengzhou].

To evaluate the effect of the implementation of emission reduction measures and the improvement in air quality during the National Traditional Games of Ethnic Minorities in Zhengzhou, a series of online instruments were used to continuously observe air pollutants and components of PM from August 5 to September 30, 2019. Three cases, including before emission reduction (August 5-24), during emission reduction (August 25 to September 18), and after emission reduction (September 19-30), were classified by the implementation of control measures. The results show that the growing concentration of PM after the cancellation of emission abatement measures (11.

Yin Yang-1 suppresses CD40 ligand-CD40 signaling-mediated anti-inflammatory cytokine interleukin-10 expression in pulmonary adventitial fibroblasts by promoting histone H3 tri-methylation at lysine 27 modification on interleukin-10 promoter.

During the pathogenesis of early pulmonary arterial hypertension (PAH), pulmonary arterial adventitial fibroblast act as an initiator and mediator of inflammatory processes that predispose vessel walls to excessive vasoconstriction and pathogenic vascular remodeling. Emerging studies report that Yin Yang-1 (YY-1) plays important roles in inflammatory response and vascular injury. Our recent study finds that activation of CD40 ligand (CD40L)-CD40 signaling promotes pro-inflammatory phenotype of pulmonary adventitial fibroblasts.

Early growth response 1 reduction in peripheral blood involving condylar subchondral bone loss.

Objectives: To detect whether early growth response 1 (EGR1) in peripheral blood leucocytes (PBLs) indicates temporomandibular joint (TMJ) osteoarthritis (OA) lesions.

Materials And Methods: Egr1 mRNA expression levels in PBLs were detected in eight malocclusion patients without temporomandibular disorder (TMD) signs and 16 malocclusion patients with clinical TMD signs with (eight) or without (eight) imaging signs of TMJ OA. Twelve 6-week-old rats were randomized to a control group and a unilateral anterior crossbite (UAC) group and were sampled at 4 weeks.

Effect of patchouli alcohol on Helicobacter pylori-induced neutrophil recruitment and activation.

Neutrophil infiltration typically occurs in Helicobacter pylori (H. pylori)-induced acute gastritis; however, this immune response fails to eradicate H. pylori in vivo.

Unraveling the Novel Protective Effect of Patchouli Alcohol Against -Induced Gastritis: Insights Into the Molecular Mechanism and .

Patchouli alcohol (PA), a natural tricyclic sesquiterpene extracted from (Blanco) Benth. (Labiatae), has been found to exhibit anti- and anti-inflammatory properties. In this study, we investigated the protective effect of PA against induced gastritis and , and determined the underlying mechanism.

Vertical contact tightness of occlusion comparison between orofacial myalgia patients and asymptomatic controls: a pilot study.

Objective: The association between occlusal contact and orofacial pain remains unclear. The aim of this study was to detect occlusal contact tightness by using a new method and to compare differences between patients and asymptomatic controls.

Methods: Fifteen female patients with orofacial myalgia and fifteen age- and sex-matched asymptomatic controls were enrolled.

Berberrubine attenuates mucosal lesions and inflammation in dextran sodium sulfate-induced colitis in mice.

Ulcerative colitis (UC) is a chronic relapsing disease without satisfactory treatments, in which intestinal inflammation and disrupted intestinal epithelial barrier are two main pathogeneses triggering UC. Berberrubine (BB) is deemed as one of the major active metabolite of berberine (BBR), a naturally-occurring isoquinoline alkaloid with appreciable anti-UC effect. This study aimed to comparatively investigate the therapeutic effects of BB and BBR on dextran sodium sulfate (DSS)-induced mouse colitis model, and explore the potential underlying mechanism.

[Mechanism of anti-Helicobacter pylori urease activity of patchouli alcohol].

To investigate the effect of patchouli alcohol on inhibiting Helicobater pylori urease activity, and its effect on expression levels of related genes, and lay the foundation for further research on the effect of patchouli alcohol on H. pylori colonization and infection. H.

Effect of Suo Quan Wan on the bladder function of aging rats based on the β-adrenoceptor.

Suo Quan Wan (SQW) has been used to treat lower urinary tract symptoms (LUTS) in elderly patients for hundreds of years in China. β-adrenoceptors (β-ARs), particularly β-adrenoceptor (β-AR), was reported to be important in the bladder dysfunction of the elderly. The present study was conducted to explore the effect of β-AR, and particularly the β-adrenoceptor, in aging rat bladder function and to test the therapeutic effect of SQW on LUTS in an aging rat model based on the β-adrenoceptor.