Guang Pu Xue Yu Guang Pu Fen Xi
February 2010
Based on the principles of organizational optics, the noninvasive tissue oxygenation saturation monitor was developed. The monitor was used to continuously monitor the changes in regional oxygen index of the thigh vastus lateralis in 101 volunteers, who performed an incremental intensity exercise on bicycle ergometer. Among the volunteers, 42 are athletes, 25 are patients whose spleens are asthenic, and the other 34 are controls.
View Article and Find Full Text PDFGuang Pu Xue Yu Guang Pu Fen Xi
January 2010
Based on the absorption spectra of hemoglobin and myoglobin in the near infrared band, the concentrations of these pigments in the biological tissues can be obtained using near infrared spectroscopy (NIRS) by detecting the intensity attenuation of the emitted light compared with the incident light. Based on the steady-state spatially resolved NIRS, the prototype for detecting the concentrations of tissue hemoglobin and myoglobin was independently developed by our group. The probe consisted of an LED light source which could emit three different wavelengths in the near infrared band, and two detectors which were placed on the same line with and at the distances of 30/40 mm to the LED.
View Article and Find Full Text PDFGuang Pu Xue Yu Guang Pu Fen Xi
March 2009
An infrared thermogram which reflects the human body surface temperature distribution can be obtained through detecting the infrared thermal radiation from each point on the human body surface. When a malignant tumor occurs in a breast, it will cause an increase in the prominent temperature in the breast surface focus region due to the abnormal blood transmission state of local focus tissue. Breast cancer can be detected through the visual analysis of the focus regions by physicians.
View Article and Find Full Text PDFGuang Pu Xue Yu Guang Pu Fen Xi
October 2008
As a non-invasive technique for measuring tissue oxygenation, near-infrared spectroscopy (NIRS) has increasing applications in detecting cerebral hypoxia-ischemia. The authors, introduced the basic principle of the NIRS oximeter developed independently by our group (TSAH-100). The authors achieved the optimal coupling between the probe and the detected cerebral tissue.
View Article and Find Full Text PDFGuang Pu Xue Yu Guang Pu Fen Xi
April 2008
Human tissue oxygen saturation (rSO2) can be monitored non-invasively and in real time by near infrared spectroscopy (NIRS) based on spatially-resolved spectroscopy. To expand the clinical applications of the NIRS oximeter developed by our group based on the above principle, the accuracy of rSO2 must be ensured and enhanced as far as possible. In the present paper, the influences of the probe configuration, especially the distance between the detectors and the wavelength discreteness of the light source, on the accuracy of rSO2 were discussed.
View Article and Find Full Text PDFObjective: To study correlation of brain hypoxia of different degrees with brain function and damage.
Methods: The brain regional oxygen saturation (rSO2) was determined by using a non-invasive near infrared spectroscopy (NIRS) technique in 15 piglets; the piglets were subjected to inhale 3% - 11% oxygen-nitrogen mixed gas through mechanical ventilation for 30 min. The piglets were divided into groups according to the level of brain rSO2 (i.
Guang Pu Xue Yu Guang Pu Fen Xi
May 2006
To avoid cerebral hypoxia caused by the imbalance between cerebral oxygen supply and consumption, regional cerebral oxygenation of patients need to be monitored at real time during cardiopulmonary bypass (CPB) surgery, and the physiological parameters can be regulated and emergent treatment can be used according to it. Using the near infrared (NIR) instrument developed by our group, cerebral oxygenation of the patients under cardiac surgery was monitored. The instrument consists of a two-wavelength near infrared light source and two near infrared detectors.
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