Publications by authors named "Yi-Yuan Lu"
MicroRNA and circRNA Expression Analysis in a Zbtb1 Gene Knockout Monoclonal EL4 Cell Line.
Front Cell Infect Microbiol
July 2021
Zinc finger and BTB domain containing 1(Zbtb1) is a transcriptional suppressor protein, and a member of the mammalian Zbtb gene family. Previous studies have shown that Zbtb1 is essential for T-cell development. However, the role of Zbtb1 in T-cell lymphoma is undetermined.
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- - Lactic acid bacteria (LAB), specifically LGG ATCC 53103, were found to enhance the diversity and abundance of intestinal microbiota in BALB/c mice, indicated by improved indices such as OTU and Shannon, while the Simpson index decreased.
- - LGG not only affected gut microbiota but also regulated the immune system by altering the distribution of various T lymphocytes and boosting the production of Th1 and Th2 cytokines, leading to a balanced immune response.
- - The study revealed that LGG treatment increased IL-17 expression and influenced the levels of regulatory T cells (Treg), suggesting a role in maintaining the balance between Th-17 and Treg cells in the immune system.