Histone deacetylase 3 suppresses the expression of SHP-1 via deacetylation of DNMT1 to promote heart failure.

Aims: Heart failure (HF) is a progressive disease with recurrent hospitalizations and high mortality. However, the mechanisms underlying HF remain unclear. The present study aimed to explore the regulatory mechanism of histone deacetylase 3 (HDAC3) and DNA methyltransferase 1 (DNMT1)/Src homology domain 2-containing tyrosine phosphatase-1 (SHP-1) axis in HF.

[CO2 fluxes in mire and grassland on Ruoergai plateau].

With closed chamber and GC technique, a comparative study was conducted on the CO2 fluxes in mire and grassland on Ruoergai plateau during the plant growth period in 2003-2005. The results showed that the mean value of the CO2 fluxes in the three years was 203.22 mg x m(-2) x h(-1) in mire and 323.

[Characteristics of nitrous oxide flux in spring wheat field ecosystem in Sanjiang Plain of Northeast China].

With static-closed-chamber and GC (Agilent 4890), the nitrous oxide (N2O) flux in spring wheat field ecosystem in the Sanjiang Plain of Northeast China was continuously observed in situ from May 2004 to October 2006. The results showed that the N2O flux presented obvious seasonal and inter-annual variation, which was mainly related with precipitation and field water management. The diurnal variation of N2O flux had correlations with the air temperature and the temperature at 5 cm underground.

[Annual dynamics of CO2, CH4, N2O emissions from freshwater marshes and affected by nitrogen fertilization].

Annual dynamics of CO2, CH4, N2O emissions from freshwater marshes and affected by nitrogen fertilization were studied in situ in Sanjiang Plain of Northeast China from June 2002 to December 2004, using the static opaque chamber-GC techniques. The results showed that there was significant seasonal and annual variation in the CO2, CH4 and N2O emissions. The ecosystem emission of CO2 reached a maximum of 779.

[Dynamics of CO2, CH4 and N2O emission fluxes from mires during freezing and thawing season].

In the Sanjiang Plain, the freezing and thawing phase have 7 - 8 months and play important role in the greenhouse gases emission. The characters of the greenhouse gases emission during freezing and thawing season in the Sanjiang Plain were studied, using the static chamber and gas chromatogram method. The results observed show that there were obvious CH4 and CO2 emissions in winter and the CH4 emission made a relatively large contribution to the total CH4 flux from the different type mires during the winter in the Sanjiang Plain.

[The changes of the soil hydrothermal condition and the dynamics of C, N after the mire tillage].

The wetlands gain increasing attention to its crucial ecological and environmental function. The tillage of the mires in the Sanjiang Plain has played the important role in regulation of the region ecological balance and climate. Prior to tillage, the mean soil temperature of the topsoil (10 cm) in mire from June to September was 12.