Publications by authors named "Yi-Yan Ding"
Article Synopsis
- Autism spectrum disorder (ASD) is linked to genetic susceptibility and environmental factors, particularly maternal infections during pregnancy which increase autism risk in children.
- Research utilizing a maternal immune activation (MIA) model showed that MIA causes autistic behaviors due to specific changes in the brain, such as microglia activation and dendritic spine abnormalities in the prefrontal cortex (PFC).
- The overexpression of NKCC1, a key protein in these processes, was identified as a contributor to these changes, and the use of the NKCC1 inhibitor bumetanide successfully reduced autistic behaviors in affected offspring.
Background: In recent years, malignant tumors have gradually become one of the main causes of death for Chinese residents, of which lung cancer ranks first in both the incidence and mortality in China.
Objective: To mine the text of traditional Chinese medicine (TCM) clinical medical cases after data cleaning, analyze it, and study the experience of TCM doctors in treating non-small cell lung cancer (NSCLC).
Methods: The applied approach was based on the data mining methods of decentralized and hierarchical system clustering of data from a drug and prescription database.