Publications by authors named "Yi-Xun Su"
Article Synopsis
- Neutrophils play a complex role in traumatic brain injury (TBI), exhibiting both protective and damaging effects that vary over time.
- Researchers utilized advanced techniques such as single-cell transcriptomics and metabolomics to explore a specific neutrophil phenotype linked to TBI outcomes, revealing a significant involvement of the FOXO1 protein.
- FOXO1-expressing neutrophils were found to contribute to worsening inflammation and depression post-TBI by regulating apoptosis and disrupting iron balance in oligodendrocytes, indicating their dual role in brain injury management.
Atoh1, Hes1 and Hes5 are crucial for normal inner ear hair cell development. They regulate the expression of each other in a complex network, while they also interact with many other genes and pathways, such as Notch, FGF, SHH, WNT, BMP and RA. This paper summarized molecular pathways that involve Atoh1, Hes1, and Hes5.
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