Publications by authors named "Yi-Xiu Gan"
Introduction: The optimal treatment for pulmonary and mediastinal metastasis of nasopharyngeal carcinoma (NPC) is still controversial, and the therapeutic effect is poor recently. In one case, we demonstrated a long-term survival after postoperative chemoradiotherapy combined with dendritic cell and cytokine-induced killer (DC-CIK) immunotherapy for pulmonary and mediastinal metastases from NPC.
Baseline Characteristics: A 53-year-old woman was admitted to our hospital in June 2008.
Article Synopsis
- The study investigates how dose distribution affects the equivalent uniform dose (EUD) model in predicting radiation-induced brain injury in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy (IMRT).
- It analyzes data from 103 patients, determining that an optimal volume-effect parameter can be found based on the max area under the curve (mAUC) from receiver operating characteristic (ROC) analyses, revealing that different volumes and dose levels influence predictive accuracy.
- The findings conclude that the volume-effect parameter in EUD varies with dose distribution, and using a critical-dose-volume EUD approach can enhance predictive capabilities compared to traditional dose/volume metrics.
Article Synopsis
- A study analyzed 221 patients with stage IA1-IIA1 cervical cancer to determine if adjuvant radiotherapy is needed after laparoscopic hysterectomy.
- Patients were divided into three groups: those receiving both surgery and radiotherapy (group A), those who had open surgery (group B), and those with laparoscopic surgery alone (group C).
- Results showed that groups A and B had significantly better 3-year local recurrence-free survival rates compared to group C, suggesting that adjuvant radiotherapy improves outcomes for early-stage cervical cancer, especially in stage IB patients.
Article Synopsis
- The study examines how half-brain delineation can help predict radiation damage in the temporal lobes of patients with nasopharyngeal carcinoma (NPC) undergoing intensity-modulated radiotherapy (IMRT).
- A retrospective analysis of 220 NPC cases showed significant differences in radiation doses received by the temporal lobes compared to half-brains, with specific dosimetric parameters demonstrating varying degrees of prediction accuracy for temporal lobe injury (TLI).
- The findings suggest that using half-brain delineation simplifies the contouring process and provides reliable estimates for TLI risk, making it a practical approach for NPC patient treatment planning.