Publications by authors named "Yi-Xiang Zhao"
Article Synopsis
- This study examined the effectiveness of using a 3D-printed guide plate in minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) surgery compared to traditional methods.
- A review of 162 patients showed that the 3D printing technique resulted in fewer needle punctures, shorter operation and fluoroscopy times, and better early recovery metrics like lower back pain and disability scores.
- The findings suggest that the 3D-printed guide offers advantages in efficiency and patient outcomes, although it did not significantly affect blood loss or overall fusion rates.
Article Synopsis
- Zinc alloys offer a promising option for orthopedic implants due to their beneficial degradation properties and physiological effects, but excessive Zn ion release can hinder osseointegration.
- This study explores two phosphate chemical conversion coatings on Zn implants—Zn-P and Ca-Zn-P—finding that while both decrease cytotoxicity, Ca-Zn-P significantly enhances osteoimmunomodulation and promotes bone healing.
- The improved outcomes with Ca-Zn-P result from mechanisms like M2 macrophage polarization and the regulation of the bone immune microenvironment, suggesting this coating could improve the performance of orthopedic implants.
Research on regulation of the immune microenvironment based on bioactive materials is important to osteogenic regeneration. Hydroxyapatite (HAP) is believed to be a promising scaffold material for dental and orthopedic implantation due to its ideal biocompatibility and high osteoconductivity. However, any severe inflammation response can lead to loosening and fall of implantation, which cause implant failures in the clinic.
View Article and Find Full Text PDF