Publications by authors named "Yi-Wun Huang"
Article Synopsis
- CD19-targeted CAR T cell therapies have transformed treatment for B-cell malignancies, but over half of patients face treatment failure due to antigen escape and low cell persistence.
- The effectiveness of these therapies is impacted by cell functionality and potential toxicities from systemic cytokines.
- A new virus-free engineering system, Quantum pBac™ (qPB), has been developed to produce dual-targeted CAR-T cells that are efficient, robust, and safe, potentially improving treatment effectiveness and accessibility.
