Publications by authors named "Yi-Wen You"
Characteristics and clinical significance of polyploid giant cancer cells in laryngeal carcinoma.
Laryngoscope Investig Otolaryngol
October 2021
Article Synopsis
- The study aimed to create a system for inducing polyploid giant cancer cells (PGCCs) and to explore their characteristics and clinical importance in laryngeal cancer.
- Researchers used paclitaxel liposomes to induce PGCCs and assessed protein expression related to cancer progression and stem cell markers through western blot analysis.
- Results indicated that the induction was successful, with significant changes in protein expression and a negative correlation between PGCC count and patient survival, suggesting PGCCs may contribute to a worse prognosis in laryngeal cancer patients.