Publications by authors named "Yi-Wen Hsu"

In Asia, some herbal preparations have been found to be adulterated with undeclared synthetic medicines to increase their therapeutic efficiency. Many of these adulterants were found to be toxic when overdosed and have been documented to bring about severe, even life-threatening acute poisoning events. The objective of this study is to develop a rapid and sensitive ambient ionization mass spectrometric platform to characterize the undeclared toxic adulterated ingredients in herbal preparations.

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Article Synopsis
  • - This study aims to create a fast and reliable method for detecting toxic mushroom compounds using mass spectrometry, eliminating the need for expert identification of mushroom types.
  • - Toxins are extracted from mushrooms using a direct electrospray probe, and results are analyzed for sensitivity, precision, and turnaround time, achieving quick identification within just one minute.
  • - The method demonstrated effective limits of detection and high accuracy, showing promise for aiding emergency healthcare providers in diagnosing and treating mushroom poisoning cases promptly.
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Background: Endometriosis is a common gynaecological disease characterized by growth of uterine endometrial tissue, outside the uterine cavity, on the ovaries, oviduct and pelvic peritoneum. Isoliquiritigenin (ISL) is a natural flavonoid isolated from the root of licorice (Glycyrrhiza uralensis) and shallot (Allium cepa). ISL has previously shown antioxidant, anti-inflammatory, anti-proliferation and anti-tumor activities.

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