Publications by authors named "Yi-Wen Gao"

Filaments driven by bound motor proteins and chains of self-propelled colloidal particles are a typical example of active polymers (APs). Due to deformability, APs exhibit very rich dynamic behaviors and collective assembling structures. Here, we are concerned with a basic question: how APs behave near a single obstacle? We find that, in the presence of a big single obstacle, the assembly of APs becomes a two-state system, APs either gather nearly completely together into a giant jammed aggregate (GJA) on the surface of the obstacle or distribute freely in space.

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Background: Soft pancreas is widely recognized as an important risk factor for the development of postoperative pancreatic fistula (POPF). Although fatty pancreas (FP) has not been formally defined as a cause of pancreatic fistula, existing research has shown that it can increase the incidence of POPF by increasing pancreatic tenderness; therefore, it may be a potential risk factor. This study aimed to discern whether FP was associated with POPF.

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Article Synopsis
  • Alzheimer's disease, marked by the buildup of amyloid β peptides, sees significant roles played by microRNAs, particularly miR-16-5p and miR-19b-3p, which are not well understood in the context of disease progression.
  • Experiments using amyloid β-treated SH-SY5Y cells demonstrated that the levels of miR-16-5p and miR-19b-3p decreased, while BACE1 protein levels increased, impacting cell viability and apoptosis.
  • The study concluded that miR-16-5p and miR-19b-3p can mitigate amyloid β-induced cellular damage by targeting BACE1, suggesting their potential as therapeutic agents for Alzheimer's disease.
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Objective: To study the risk factors for elevated serum total bile acid (TBA) in preterm infants.

Methods: A retrospective analysis was performed for the clinical data of 216 preterm infants who were admitted to the neonatal intensive care unit. According to the presence or absence of elevated TBA (TBA >24.

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Objective: To compare the incidences of Y chromosome microdeletion between patients with azoospermia or severe oligozoospermia with varicocele( VC) and those without VC and investigate the etiopathogenisis of their infertility.

Methods: We included 137 VC patients in group A(70 with azoospermia as group A1 and 67 with severe oligozoospermia as group A2),135 non-VC patients in group B(69 with azoospermia as group B1 and 66 with severe oligozoospermia as group B2),and 30 normal fertile men as controls in group C. We detected Y chromosome microdeletion in different groups using multiplex PCR.

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Objective. Hypertension is one of the most common cardiovascular disorders with high mortality. Here we explored the antihypertension effects of Huanglian Jiedu Decoction (HJD) on thoracic aorta gene expression in spontaneous hypertensive rats.

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