Longitudinal non-cystic fibrosis trends of pulmonary disease from 2010 to 2017: spread of the "globally successful clone" in Asia.

Background: (MAB) has emerged as the predominant pulmonary non-tuberculous mycobacterial pathogen in parts of Asia, including Taiwan. The reasons for the significant increase in MAB infections in the non-cystic fibrosis (CF) populations are poorly understood. The study aimed to elucidate whether this increase is related to the spread of the globally successful clone of MAB.

Comparing the Utilities of Different Multilocus Sequence Typing Schemes for Identifying Outbreak Strains of subsp. .

Outbreaks of infections by , particularly subspecies , are increasingly reported worldwide. Several multilocus sequence typing (MLST) protocols for grouping international outbreak strains have been developed but not yet directly compared. Using the three-gene (, , and ), seven-gene (, , , , , , and ) and thirteen-gene (all of the preceding genes plus , , and ) MLST schemes, we identified 22, 38, and 40 unique sequence types (STs), respectively, among a total of 139 nonduplicated isolates.

Synergism of Rifabutin with Clarithromycin, Imipenem, and Tigecycline against the Complex.

Infections caused by the difficult-to-treat bacterium are increasing in frequency. Rifabutin, in contrast to rifampin, appears to be active against , especially against clarithromycin-resistant strains. However, explorations for potential synergy between rifabutin and available antimicrobials are currently limited.

Evaluation of Povidone-Iodine and Chlorhexidine against Outbreak and Nonoutbreak Strains of Mycobacterium abscessus Using Standard Quantitative Suspension and Carrier Testing.

Povidone-iodine (PI) and chlorhexidine (CHX) are widely used antiseptics active against conventional , , species, and viruses, but their efficacy against remains unproven. We determined the potency of alcoholic PI and CHX against subsp. (ATCC 19977), subsp.