Publications by authors named "Yi-Ting Chu"

Article Synopsis
  • Exposure to hypoxia in neonatal Sprague-Dawley rats led to significant kidney damage, including higher levels of stress markers and reduced body weight compared to those in normal oxygen levels.* -
  • The study found increased protein levels related to hypoxia, inflammation, and cell death in the kidneys of rats subjected to hypoxic conditions.* -
  • Histological examination revealed kidney structural issues like glomerular atrophy and renal fibrosis, highlighting the serious impact of early postnatal hypoxia on organ health.*
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Background: Aminophylline use and the association between clinical outcomes and therapy timing have been less investigated. The objective of this study was to determine the efficacy of early aminophylline use (within the first two days of life) in premature infants.

Method: A retrospective observational cohort of infants weighing <1500 g and <30 weeks of gestational age at Kaohsiung Veterans General Hospital received aminophylline either within the first two days of life (EA, early aminophylline group), after the third day of life (LA, late aminophylline group), or without aminophylline during the first month of life (WA, without aminophylline group).

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Article Synopsis
  • Severe hyper-catecholaminergic states can lead to heart failure and cardiac fibrosis, but the effects of beta-blockade in these conditions are not well understood.
  • This study examined the impact of various dosages of propranolol on rats experiencing hyper-acute catecholamine-induced heart failure, revealing that low-dose propranolol (1 mg/kg) led to better survival rates compared to higher doses and catecholamine-only groups.
  • Findings suggested that catecholamine-induced heart failure activates pre-fibrotic pathways through FGF-23 upregulation, and low-dose propranolol improved cardiac function by reducing FGF-23 levels and enhancing hemodynamic parameters.
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In most studies describing the preparation of Cu2O crystals of various morphologies, the particle sizes are normally hundreds of nanometers to micrometers due to rapid particle growth, so they are not exactly nanocrystals. Here we report surfactant-free formation of sub-100 nm Cu2O nanocrystals with systematic shape evolution from cubic to octahedral structures by preparing an aqueous mixture of Cu(OAc)2, NaOH, and N2H4 solution. Adjustment of the hydrazine volume enables the particle shape control.

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In this work, palladium tripod nanocrystals have been synthesized by mixing an aqueous solution of cetyltrimethylammonium bromide (CTAB) surfactant, Na(2)PdCl(4), copper acetate, and ascorbic acid at 30 °C for 3 h. Addition of a small amount of copper ion source is critical to the formation of these tripods with a pod length reaching 100 nm. The incorporation of Cu atoms into the Pd tripods has been verified.

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