Publications by authors named "Yi-Shuo Su"
Xeno-free culture and proliferation of hPSCs on 2D biomaterials.
Ting Wang Tao Yu Chang-Yen Tsai Zhao-Yu Hong Wen-Hui Chao Yi-Shuo Su Suresh Kumar Subbiah Shih-Tien Hsu
Prog Mol Biol Transl Sci
September 2023
Article Synopsis
- - Human pluripotent stem cells (hPSCs), which include human embryonic and induced pluripotent stem cells, have unlimited growth potential, unlike adult stem cells that face aging issues.
- - Culturing hPSCs requires specific materials and surfaces, avoiding traditional plastic dishes used for adult stem cells, to ensure they can grow without feeder layers while maintaining their ability to differentiate into various cell types.
- - The review highlights various biomaterials, such as recombinant ECM proteins and advanced synthetic surfaces, that support hPSC growth under xeno-free conditions, reducing the risk of contamination and enhancing their clinical applications.