Licochalcone-E induces caspase-dependent death of human pharyngeal squamous carcinoma cells through the extrinsic and intrinsic apoptotic signaling pathways.

The aim of the present study was to investigate licochalcone-E (Lico-E)-induced apoptosis and the associated apoptotic signaling pathway in FaDu cells, a human pharyngeal squamous carcinoma cell line. Treatment with Lico-E exhibited significant cytotoxicity on FaDu cells in a concentration-dependent manner. The IC value of Lico-E in FaDu cells was ~50 µM.

Inhibitory effect of Korean Red Ginseng on melanocyte proliferation and its possible implication in GM-CSF mediated signaling.

Korean Red Ginseng (KRG) has been reported to exert anticancer, anti-oxidant, and anti-inflammatory effects. However, there has been no report on the effect of KRG on skin pigmentation. In this study, we investigated the inhibitory effect of KRG on melanocyte proliferation.

Placement angle effects on the success rate of orthodontic microimplants and other factors with cone-beam computed tomography.

Introduction: The purpose of this study was to evaluate the effect of placement angles on the success rate of orthodontic microimplants and other factors with cone-beam computed tomography images.

Methods: We examined 228 orthodontic microimplants implanted into the maxillary buccal alveolar bone of 130 patients (33 men, 97 women) with malocclusion. Vertical placement angle, horizontal placement angle, root proximity, and cortical bone thickness were measured, and the correlations between these measurements and orthodontic microimplant success rates and the correlations among the measurements were evaluated.