Publications by authors named "Yi-Qiao Gao"
Saikosaponin d (SSd) is a major hepatoprotective component of saikosaponins derived from , which was also linked to hepatotoxicity. Previous studies have demonstrated that caspases play a key role in SSd-induced liver cell death. Our and studies also showed that treatment with caspase inhibitor z-VAD-fmk could significantly reduce the L02 hepatocyte cells death and lessen the degree of liver damage in mice caused by SSd.
View Article and Find Full Text PDFArticle Synopsis
- * A study on male rats revealed that realgar NPs led to increased liver enzyme levels and fat accumulation, indicating hepatotoxicity.
- * Metabolomics analysis identified significant changes in serum and liver metabolites, helping differentiate the effects of realgar NPs from other treatments and contributing to understanding nanotoxicity.