Publications by authors named "Yi-Ning Dai"
Pulmonary infection is highly prevalent in patients with acute myocardial infarction undergoing percutaneous coronary intervention. However, the potential mechanism is not well characterized. Myocardial ischemia-reperfusion injury (MIRI) induces acute lung injury (ALI) related to pulmonary infection and inflammation.
View Article and Find Full Text PDFBackground: Concurrent non-alcoholic fatty liver disease (NAFLD) is common in patients with chronic HBV infection. But the impact of fatty liver on the histologic progression of HBV infection remains controversial.
Methods: Consecutive HBV-infected patients who underwent liver biopsy between 2016 and 2021 were included.
Article Synopsis
- Recently, nonalcoholic fatty liver disease (NAFLD) has been rebranded as metabolic-associated fatty liver disease (MAFLD), excluding certain non-obese individuals from its definition.
- The study analyzed the histological differences between MAFLD and non-MAFLD groups in biopsy-proven NAFLD patients, focusing on metabolic dysfunction indicators.
- Results showed that MAFLD patients had a greater NAFLD activity score and more severe hepatic steatosis compared to non-MAFLD patients, while no significant differences in other histological features were found between the groups.
Background: Infections are not common but important in patients with acute myocardial infarction, and are associated with worse outcomes. Infection was proved to be associated with the use of proton pump inhibitor (PPI) in several cohorts. It remains unclear whether PPI usage affects infection in patients with acute myocardial infarction.
View Article and Find Full Text PDFBackground: In patients with stable coronary artery disease, low DBP is associated with an increased risk of myocardial infarction and cardiovascular death, but its association with clinical outcomes in patients with acute myocardial infarction undergoing percutaneous coronary intervention (PCI) is unknown.
Methods: Consecutive patients with ST-segment elevation myocardial infarction (STEMI) undergoing PCI from January 2010 to June 2016 were enrolled. The patients were divided into five groups according to the quintiles of DBP at admission.
Infections increase the risk of poor outcomes in patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI). However, predicting patients at a high risk of developing infection remains unclear. Moreover, the value of N-terminal probrain natriuretic peptide (NT-proBNP) for predicting infection is still unknown.
View Article and Find Full Text PDFBackground And Aims: Although ticagrelor exerts an antibacterial activity, its effect on infections in patients with ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI) is unclear. We aimed to assess whether ticagrelor and clopidogrel affect infections in these patients during hospitalization.
Methods: A total of 2116 consecutive patients with STEMI undergoing PCI were divided into the ticagrelor (n = 388) and clopidogrel (n = 1728) groups.
Article Synopsis
- * The model evaluated data from 914 suspected COVID-19 pneumonia cases, assessing variables like epidemiological features, clinical symptoms, and imaging results.
- * Results showed the model had a high accuracy of 87%, a sensitivity of 83.82%, and specificity of 89.57%, indicating its effectiveness for early detection and treatment of COVID-19 pneumonia.
Background: Inspiratory muscle strength is associated with pneumonia in patients after surgery or those with subacute stroke. However, inspiratory muscle strength in patients with acute myocardial infarction (AMI) has not been studied.
Objective: To evaluate the predictive value of inspiratory muscle strength for pneumonia in patients with AMI.
Article Synopsis
- The study aimed to create a fast screening model to early detect novel coronavirus pneumonia (NCP) in a population from Zhejiang, China.
- It involved 880 individuals suspected of having NCP and utilized various predictors like epidemiological data, clinical signs, and lab results, achieving a high accuracy of 0.920.
- The developed models showed strong sensitivity and specificity, proving to be practical and cost-effective tools for predicting NCP early, especially amid a widespread outbreak.
Uncommonly high rates of pneumonia in patients with acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (PCI) have been observed during recent years. Inspiratory muscle training (IMT) could reduce pneumonia in patients undergoing coronary artery bypass grafting and other cardiac surgeries. The relationship between IMT and AMI is unknown.
View Article and Find Full Text PDFBackground: Epithelioid angiosarcoma is a vascular neoplasm that is among the most aggressive subtypes of sarcomas. Its involvement in the gastrointestinal tract is rare. We here report a case of multifocal gastrointestinal epithelioid angiosarcomas presenting with gastrointestinal bleeding.
View Article and Find Full Text PDFStatins have been shown to reduce the risk of post-contrast acute kidney injury (PC-AKI) in patients undergoing percutaneous coronary intervention (PCI). However, the preventive effect of rosuvastatin versus atorvastatin on PC-AKI in patients with ST-segment elevation myocardial infarction (STEMI) undergoing PCI remains unclear. Patients with STEMI undergoing PCI between January 2010 and May 2016 were consecutively enrolled.
View Article and Find Full Text PDFBackground: Although rare, infection in patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI) significantly increases mortality. Therefore, it is important to identify patients at high risk of infection. We aimed to validate the value of the Canada Acute Coronary Syndrome (C-ACS) risk score for predicting infection in such patients.
View Article and Find Full Text PDFArticle Synopsis
- * The study analyzed the proteomic profiles of CHB patients with different levels of liver fibrosis to identify potential serum biomarkers for detecting the critical S2 stage, involving 90 CHB patients and additional validation groups.
- * A total of 139 proteins showed significant expression differences across fibrotic stages, with five candidates identified as promising biomarkers, particularly ficolin-2 (FCN2) and carboxypeptidase B2 (CPB2), which require further investigation for their
Article Synopsis
- Tuberculous meningitis (TBM) is a severe infection of the brain's protective membranes, with high rates of illness and death, making it difficult to diagnose against other meningitis types.
- Researchers conducted a study analyzing cerebrospinal fluid (CSF) samples from patients with TBM and other types of meningitis using advanced mass spectrometry to identify unique metabolites.
- The analysis revealed distinct metabolic profiles between TBM and other meningitis forms, uncovering potential biomarkers for better differentiation and diagnosis of TBM.
Article Synopsis
- Tuberculous meningitis (TBM) is a severe form of central nervous system tuberculosis with a notably poor prognosis, primarily assessed by the Glasgow Outcome Scale at discharge.
- A study of 45 TBM patients revealed that 77.8% had a good prognosis, while 22.2% faced a poor prognosis, with key factors such as old age, disturbed consciousness, and hydrocephalus linked to worse outcomes.
- Multivariate analysis identified old age and hydrocephalus as significant independent predictors of poor prognosis, highlighting the need for timely and special care for affected patients.
Objectives:: Esophageal leiomyoma is the most common benign tumor of the esophagus, and it originates from mesenchymal tissue. This study analyzed the clinicopathological characteristics of esophageal leiomyoma and aimed to evaluate the role of endoscopic ultrasonography in the diagnosis and treatment selection for these lesions.
Methods:: Two hundred and twenty-five patients who had suspected esophageal leiomyomas in endoscopic ultrasonography were enrolled at the Endoscopy Center of The First Affiliated Hospital, Zhejiang University from January 1st, 2009 to May 31th, 2015.
Article Synopsis
- Peliosis hepatis (PH) is a rare liver condition that features blood-filled cavities, making it difficult to distinguish from other types of liver lesions during imaging.
- The report discusses two cases where patients showed liver lesions on ultrasound and CT scans, without any previous liver issues or drug use.
- Diagnosing PH involved liver biopsy and laparoscopy, revealing sinusoidal dilatations, and both patients showed good recovery after follow-up for a year.
Objective: Primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), autoimmune hepatitis (AIH) and immunoglobulin G4 related cholangitis represent the major autoimmune liver diseases (AILD). However, the relationship between AILD incidence and socioeconomic development levels is yet to be explored.
Results: A total of 43 studies were included.
Background: Non-alcoholic fatty liver disease (NAFLD) is a great health burden. Neuregulin 4 (Nrg4) is a recently identified secret factor that may be associated with NAFLD.
Aim: To investigate the association between serum Nrg4 level and NAFLD by conducting a case-control study.
Recent animal studies support close associations of Periostin with hepatosteatosis and steatohepatitis. This study is to evaluate the role of serum periostin in non-alcoholic fatty liver disease (NAFLD). A hospital-based age-/sex-matched case-control study was conducted.
View Article and Find Full Text PDFPurpose: We aim to investigate the association between angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs) therapy and colorectal cancer (CRC) by conducting a systematic review with meta-analysis.
Methods: Literature was searched on PubMed, Scopus, and the Cochrane library to identify relevant studies evaluating ACEIs/ARBs therapy and risk of CRC incidence or survival of CRC patients. Pooled risk ratio (RR) with 95% confidence intervals was calculated for the association between ACEIs/ARBs and CRC risk and mortality.