[The Correlation Between MicroRNAs in Serum and the Extent of Liver Injury].

Objectives: To investigate the correlation between the absolute quantification of the microRNAs (miR-122, miR-451, miR-92a, miR-192) in serum during acute liver injury and the extent of liver injury on rat models of CCl induced acute liver injury and mice models of acetaminophen (APAP) induced acute liver injury. Furthermore, to investigate the correlation between the absolute quantification of microRNAs in serum and the drug induced liver injury pathological scoring system (DILI-PSS).

Methods: The acute liver injury model in rat by CCl (1.

[Effects of Msp on the Proliferation, Migration and Invasion of Human Non-small Cell Lung Cancer Cells].

Objectives: To determine the effects of macrophage stimulating protein (Msp) on the proliferation, migration and invasion of human non-small cell lung cancer cells PC14.

Methods: The eukaryotic expression vector for was constructed and transfected into Msp(-)and RON(-)human non-small cell lung cancer cells PC14. The expression of mRNA in PC14 cells was observed by RT-PCR.