Publications by authors named "Yi-Min Tang"

Article Synopsis
  • The study investigated the efficacy and safety of Shufeng Jiedu (SFJD) capsules for managing mild to moderate COVID-19 symptoms through a randomized, double-blind, placebo-controlled trial conducted in China from May to December 2022.
  • A total of 407 participants completed the trial, with those taking SFJD experiencing faster symptom relief, with a median time of 7 days compared to 8 days for the placebo group.
  • The SFJD group also showed significant reductions in fever and headache symptoms, and no serious adverse events occurred during the trial.
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Background: Kawasaki disease (KD) is an acute type of systemic vasculitis involving small to medium-sized muscular arteries and outbreaks during childhood. KD can cause myocardial ischemia, infarction, and sudden cardiac arrest. We present a case of a young adult survivor of out-of-hospital cardiac arrest as late KD sequelae.

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Article Synopsis
  • Hepatitis B virus (HBV) infections in infants are primarily transmitted from mother to child during birth, and current tests cannot reliably determine if this transmission has occurred.
  • A study conducted on 5999 pregnant women in Shenzhen City from 2011 to 2016 found that a significant percentage of their newborns had various HBV markers in their blood, which correlated with the mother's HBV status.
  • The research concluded that a high HBV DNA titer in umbilical cord blood and the presence of HBeAg in mothers are strong indicators of potential HBV mother-to-child transmission.
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  • - The study investigates the role of miR-638 in osteosarcoma (OS), finding that it is downregulated in cancerous tissues compared to noncancerous tissues and has a lower DNA copy number in OS.
  • - Experimental results show that miR-638 inhibits cell growth in OS, and its effects are linked to its ability to target and suppress the gene PIM1, which is overexpressed in OS tissues.
  • - Higher levels of PIM1 correlate with poor survival outcomes in OS patients, suggesting that miR-638 acts as a tumor suppressor by downregulating PIM1 expression.
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A new method of preparing Itraconazole (C35H38Cl2N8O4), a synthetic triazole antifungal agent, was developed using supercritical carbon dioxide (SC CO2) while eliminating the use of toxic solvents. Dissolution amounts of the product were measured in gastric fluid and compared to those of conventional drug formulations. Different operating conditions (five levels of treatment temperature ranging between 110-140 degrees C, four levels of treatment pressure ranging between 30-400 atm, and four different treatment times ranging from 10-60 minutes) were tested in order to produce a desired Itraconazole product, which does not degrade during the product formation and has the highest extent of dissolution in gastric fluid after one hour.

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Spermatozoa of 10, 15 and 20-wk-old KM mice were frozen and stored at--196 degrees C. After thawing, intact superovulation oocytes were inseminated in vitro with relative high motility frozen/thawed mouse spermatozoa. Some 2-cell embryos obtained by in vitro fertilization were transferred to pseudopregnant recipients and 47%-56% of them developed into live-born offspring.

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