Publications by authors named "Yi-Meng Lin"
Article Synopsis
- - The study aimed to investigate how electroacupuncture (EA) preconditioning affects cell death (apoptosis) and levels of reactive oxygen species (ROS) in rats experiencing myocardial ischemia/reperfusion injury (MIRI).
- - Eighty male Wistar rats were divided into four groups, with the EA group receiving daily acupuncture treatment before inducing MIRI, which was achieved by blocking blood supply to the heart for 20 minutes followed by reperfusion.
- - Results showed that the EA treatment significantly reduced harmful changes associated with MIRI, such as higher arrhythmia scores, CK-MB levels, and ROS, suggesting that EA may protect the heart by regulating the ROS-related apoptosis pathway.
The effects of long-term nitrate therapy are compromised due to protein S-Nitrosylation, which is mediated by nitric oxide (NO). This study is to determine the role of Akt S-Nitrosylation in the recovery of heart functions after ischaemia. In recombinant Akt protein and in HEK293 cells, NO donor decreased Akt activity and induced Akt S-Nitrosylation, but was abolished if Akt protein was mutated by replacing cysteine 296/344 with alanine (Akt-C296/344A).
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