Publications by authors named "Yi-Lei Nie"
Article Synopsis
- - A chemical investigation of a marine-derived actinomycete strain, Micromonospora sp. FIM05328, led to the discovery of a new 26-membered polyene macrolactam metabolite called FW05328-1, alongside a known compound called aurodox.
- - The structures of both compounds were determined using advanced analysis techniques like 1D and 2D NMR and HR-TOF-MS, supported by literature data.
- - Both compounds showed promising antiproliferative effects against specific human tumor cell lines (KYSE30, KYSE180, and EC109), but did not exhibit any antibacterial activity against the tested bacteria or fungi.
Strain FIM06054 was isolated from a marine sponge sample collected from the East China Sea and was characterised as a strain of Verrucosispora genus on the basis of its 16S rRNA gene sequence. One new compound, FW054-1 (1), together with a known aminofuran compound proximicin A (2), was isolated from the culture broth of Verrucosispora sp. FIM06054.
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