Publications by authors named "Yi-Kai Zhao"
The application of biomarkers to study the molecular composition of soil organic matter (SOM) can be used to analyze the source and degradation of SOM and reveal the stability mechanism of soil organic carbon (SOC) at the molecular level. In order to further clarify the effects of different land use patterns (farmland, grassland, and forest) on the molecular composition of SOM, the changes in molecular composition of organic matter (free lipids, cutin, suberin, and lignin) on a global scale were studied using a meta-analysis method. The results showed that there were significant differences in the molecular composition of organic matter under different land use patterns.
View Article and Find Full Text PDFArticle Synopsis
- Research identifies the presence of the fungus Aspergillus sydowii within tumors of lung adenocarcinoma (LUAD) patients, highlighting the significance of the intratumor mycobiome in cancer development.
- Experiments on lung cancer mouse models show that A. sydowii accelerates tumor growth by activating certain immune cells (MDSCs) through the IL-1β signaling pathway, leading to weakened immune responses.
- The study indicates that higher levels of A. sydowii in human tumors correlate with immune suppression and worse outcomes for patients, suggesting potential for targeting this fungus to improve treatment for LUAD.
Arctiin is the most abundant bioactive compound contained in the Arctium lappa plant. In our previous study, we isolated one single bacterium capable of bioconverting arctigenin, an aglycone of arctiin, to 3'-desmethylarctigenin (3'-DMAG) solely. However, to date, a specific bacterium capable of producing other arctiin metabolites has not been reported.
View Article and Find Full Text PDF