Publications by authors named "Yi-Jia Shao"
J Hum Hypertens
December 2019
Article Synopsis
- A study evaluated the effects of remote ischemic preconditioning (RIPC) on blood pressure (BP) and endothelial function in hypertensive patients.
- Fifteen patients underwent a 30-day RIPC regimen with significant reductions in both systolic and diastolic BP, along with improvements in microvascular endothelial function measured by the reactive hyperemia index (RHI).
- Additionally, RIPC led to an increase in circulating hSDF-1α levels, which correlated with the observed reductions in BP and improved endothelial function, suggesting RIPC as a potential treatment for hypertension.
Chin J Integr Med
December 2018
Article Synopsis
- The study aims to determine if berberine can enhance the endothelial repair abilities of early endothelial progenitor cells (EPCs) from prehypertensive individuals by boosting CXCR4 signaling.
- The researchers isolated EPCs from both prehypertensive and healthy subjects and tested their reendothelialization capabilities in a mouse model, observing various signaling pathways involved in their function.
- Results showed that berberine treatment improved CXCR4/JAK-2 signaling in EPCs, significantly enhancing their restoration capacity in vivo, suggesting berberine could be a potential preventive treatment for heart disease related to prehypertension.
