Watt-level single-frequency tapered amplifier laser using a narrowband interference filter.

We demonstrate a tunable external cavity tapered amplifier laser (ECTAL) using a narrowband interference filter as the wavelength discriminator. The laser is tunable over a wavelength range from 1006 to 1031 nm with an output power of ∼1  W. The amplified stimulated emission of the laser system is suppressed to better than 32 dB.

Functional importance of apolipoprotein A5 185G in the activation of lipoprotein lipase.

Background: Apolipoprotein A5 (APOA5) over-expression enhances lipolysis of triglyceride (TG) through stimulation of lipoprotein lipase (LPL) activity; however, an APOA5 G185C variant was found associated with hypertriglyceridemia. The aim of this study was, therefore, to explore the importance of APOA5 185GG in the activation of LPL.

Methods: A fragment containing mature human APOA5 cDNA was obtained by RT-PCR and subcloned into pET-15b vector.