Publications by authors named "Yi-Hao Zhou"
Objective: Oxidative stress is an important factor mediating the pathologic progression of many diseases. In recent years, the antioxidant effects of acupuncture have been gradually confirmed. However, bibliometric analysis in this field, which is still lacking.
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- Cells react to DNA damage through responses like DNA repair or programmed cell death (apoptosis), but the factors influencing these choices are not well understood.
- The protein ANGPTL8, which is usually involved in lipid metabolism, also plays a key role in guiding cells towards apoptosis instead of repair when faced with DNA damage.
- ANGPTL8 interacts with a protein called PARP1, promoting apoptosis by enhancing PARP1's accumulation on damaged DNA, while its own levels decrease after DNA damage to prevent excessive toxicity.
Herein, the assembly of 3D uniform gear-like architectures is demonstrated with a tobacco mosaic virus (TMV) disk as a building block. In this context, the intrinsic behavior of the TMV disk that promotes its assembly into nanotubes is altered by a synergistic effect of dual functional modifications at the 53rd arginine mutation and the introduction of lysine groups in the periphery at 1st and 158th positions of the TMV disk, which results in the formation of 3D gear-like superstructures. Therein, the 53rd arginine moiety significantly strengthens the linkage between TMV disks in the alkaline environment through hydrogen bond interactions.
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