Publications by authors named "Yi-Feng Zha"
Objectives: Opioid-free anaesthesia (OFA) has emerged as a promising approach for mitigating the adverse effects associated with opioids. The objective of this study was to evaluate the impact of OFA on postoperative nausea and vomiting (PONV) following video-assisted thoracic surgery.
Design: Single-centre randomised controlled trial.
Article Synopsis
- Senkyunolide I (SEI), derived from Ligusticum Chuanxiong, may help reduce lung injuries caused by sepsis in mice, affirming its protective role against such conditions.
- Treatment with SEI led to significant reductions in protein levels and neutrophil infiltration in the lung, as well as lowered inflammation markers (TNF-α, IL-1β, IL-6) in plasma and tissues.
- SEI's protective effects were linked to inhibited activation of inflammatory pathways, demonstrated by decreased phosphorylation of specific proteins related to inflammation, and fewer neutrophils observed in treated mice compared to control groups.
Background: Acute kidney injury is a common clinical comorbidity and early diagnosis is crucial for improving prognosis, but there is still no ideal biomarker for early diagnosis.
Material And Methods: miRNA microarray was used for detecting miRNA in kidney subjected to renal ischemia-reperfusion injury 12 h after reperfusion. Real-time PCR was performed to validate the results of microarray.