Publications by authors named "Yi-Fan Chi"

Article Synopsis
  • * The study investigated how Jagged1-Notch signaling is affected by Ang II in the context of this impaired angiogenesis and cardiac hypertrophy using male mice and specific treatments.
  • * Results indicated that Ang II caused significant cardiac hypertrophy and reduced angiogenesis, while the protein Jagged1 increased but its gene expression decreased in the heart tissue, suggesting a complex interaction in the disease process.
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Objectives: To determine risk factors associated with postoperative hypoxemia after surgery for acute type A aortic dissection.

Methods: We retrospectively analyzed the clinical data of 192 patients with acute type A aortic dissection who underwent surgery in Qingdao Municipal Hospital, Medical College of Qingdao University, Qingdao, China between January 2007 and December 2013. Patients were divided into hypoxemia group (n=55) [arterial partial pressure of oxygen (PaO2)/fraction of inspired oxygen (FiO2) ≤ 200 mm Hg] and non-hypoxemia group (n=137) [PaO2/FiO2 > 200 mm Hg].

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Objective: To investigate the related factors and pathogens of ventilator-associated pneumonia (VAP) after heart surgery so as to provide evidences for clinical prevention and therapy.

Methods: In total 1,688 cases were collected from January 2004 to January 2011. Overall 105 patients developed VAP.

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Objective: Levosimendan is a calcium sensitizer that enhances myocardial contractility without increasing myocardial oxygen use. Limited data are available on its renal-protective effect, and no statistically significant effects have been found. A meta-analysis was conducted for randomized studies to show whether perioperative levosimendan use could reduce acute kidney injury (AKI) in patients undergoing cardiac surgery.

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Objective: To investigate the related factors and pathogens of ventilator-associated pneumonia (VAP) after heart surgery.

Methods: VAP was diagnosed in 105 patients out of 1688 cases (6.2%) who underwent heart surgery in our department between January 2004 and January 2011.

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