Effect of subdural muscle packing in repairing dura mater after retrosigmoid craniotomy.

Objective: This study was performed to evaluate a new type of autologous muscle tamponade to repair dura mater that has undergone dural defects to prevent cerebrospinal fluid leakage or subcutaneous fluid accumulation.

Methods: Three hundred thirty-two patients who underwent retrosigmoid craniotomy were selected and divided into two groups: bone window craniotomy and bone flap craniotomy. Each group was further divided into two groups: artificial dura repair and autologous muscle repair.

Uhrf2 deletion impairs the formation of hippocampus-dependent memory by changing the structure of the dentate gyrus.

Ubiquitin-like with PHD and ring finger domains 2 (Uhrf2) is distributed in many brain regions, including the cortex and hippocampus. Decreased Uhrf2 expression is involved in neurodegenerative disease. A recent study showed Uhrf2 deletion impaired spatial memory; however, the mechanism remains elusive.