Publications by authors named "Yi-En Ku"
Int J Antimicrob Agents
July 2024
Article Synopsis
- The study aimed to create machine learning models to predict nephrotoxicity caused by colistin in patients with multidrug-resistant Gram-negative infections, highlighting its impact on hospital stays and mortality.
- Data from 1392 patients across different time periods were analyzed, revealing that 36.4% to 40.9% of patients experienced nephrotoxicity, with categorical boosting methods performing best in prediction accuracy.
- Key risk factors identified included the duration and dosage of colistin, as well as certain blood markers, suggesting that adjusting dosage guidelines could help mitigate risks, and more studies are needed to validate these findings.
