Publications by authors named "Yi-Dan Qiao"

Desmoplastic small round-cell tumors (DSRCT) frequently develop in the retroperitoneum, pelvis, omentum, and mesentery. Here, we present an unusual case of primary DSRCT in the liver. The patient was an 11-year-old boy with multiple solid masses in the liver parenchyma.

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In this era of immune checkpoint inhibitors, inflammatory adverse events of anti-cancer therapies continue to pose a major challenge. Glucocorticoids, as the mainstay, were limited by serious side effects. Glucocorticoids induce myeloid-derived suppressor cells (MDSCs), and lactoferrin-induced polymorphonuclear MDSCs (PMN-MDSCs) were shown to relieve inflammatory conditions.

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Article Synopsis
  • CD45CD71 erythroid cells in hepatocellular carcinoma (HCC) tissues are elevated compared to surrounding and circulating areas, revealing their potential role in the tumor environment.
  • These cells inhibit T cell activity through mechanisms involving reactive oxygen species, IL-10, and TGF-β, showing a stronger suppressive effect than myeloid-derived suppressor cells.
  • The presence of CD45CD71 erythroid cells in HCC is associated with disease-free and overall survival, indicating they might be useful as biomarkers for predicting the recurrence of this type of cancer.
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